Diverse Sphingolipid Species Harbor Different Effects on Ire1 Clustering

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Diverse Sphingolipid Species Harbor Different Effects on Ire1 Clustering

Endoplasmic reticulum (ER) function is dedicated to multiple essential processes in eukaryotes, including the processing of secretory proteins and the biogenesis of most membrane lipids. These roles implicate a heavy burden to the organelle, and it is thus prone to fluctuations in the homeostasis of...

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Bibliographic Details
Main Authors:	Bieniawski, Mark A., Stevens, Kofi L.P., Witham, Christopher M., Steuart, Robert F. L., Bankaitis, V.A., Mousley, Carl J.
Format:	Journal Article
Language:	English
Published:	MDPI 2022
Subjects:	Science & Technology Life Sciences & Biomedicine Physical Sciences Biochemistry & Molecular Biology Chemistry, Multidisciplinary Chemistry unfolded protein response (UPR) Ire1 sphingolipids Kes1 Osh4 UNFOLDED PROTEIN RESPONSE STRESS SENSOR IRE1 SACCHAROMYCES METABOLISM ACTIVATION CERAMIDES MECHANISM STRAINS SIGNALS BINDING Protein Serine-Threonine Kinases Sphingolipids Unfolded Protein Response Endoplasmic Reticulum Stress Cluster Analysis Oxysterols Endoribonucleases
Online Access:	http://hdl.handle.net/20.500.11937/96046

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