Mechanisms of Cancer-Associated Thrombosis: Role of Cancer-Derived Exosomes
This thesis investigated the effect of pancreatic cancer-derived exosomes on cells that are known to play roles in thrombosis. Together, the results demonstrate that PDEx have a range of effects on neutrophils, platelets and endothelial cells. Overall they can modulate the function of these cells to...
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| Format: | Thesis |
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Curtin University
2024
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| Online Access: | http://hdl.handle.net/20.500.11937/95952 |
| _version_ | 1848766063282487296 |
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| author | Abdol Razak, Norbaini Binti |
| author_facet | Abdol Razak, Norbaini Binti |
| author_sort | Abdol Razak, Norbaini Binti |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | This thesis investigated the effect of pancreatic cancer-derived exosomes on cells that are known to play roles in thrombosis. Together, the results demonstrate that PDEx have a range of effects on neutrophils, platelets and endothelial cells. Overall they can modulate the function of these cells to have procoagulant properties, suggesting that PDEx has a significant function in promoting thrombosis and can potentially be targeted for therapeutic intervention cancer-associated thrombosis. |
| first_indexed | 2025-11-14T11:45:11Z |
| format | Thesis |
| id | curtin-20.500.11937-95952 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:45:11Z |
| publishDate | 2024 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-959522024-09-25T07:22:15Z Mechanisms of Cancer-Associated Thrombosis: Role of Cancer-Derived Exosomes Abdol Razak, Norbaini Binti This thesis investigated the effect of pancreatic cancer-derived exosomes on cells that are known to play roles in thrombosis. Together, the results demonstrate that PDEx have a range of effects on neutrophils, platelets and endothelial cells. Overall they can modulate the function of these cells to have procoagulant properties, suggesting that PDEx has a significant function in promoting thrombosis and can potentially be targeted for therapeutic intervention cancer-associated thrombosis. 2024 Thesis http://hdl.handle.net/20.500.11937/95952 Curtin University fulltext |
| spellingShingle | Abdol Razak, Norbaini Binti Mechanisms of Cancer-Associated Thrombosis: Role of Cancer-Derived Exosomes |
| title | Mechanisms of Cancer-Associated Thrombosis: Role of Cancer-Derived
Exosomes |
| title_full | Mechanisms of Cancer-Associated Thrombosis: Role of Cancer-Derived
Exosomes |
| title_fullStr | Mechanisms of Cancer-Associated Thrombosis: Role of Cancer-Derived
Exosomes |
| title_full_unstemmed | Mechanisms of Cancer-Associated Thrombosis: Role of Cancer-Derived
Exosomes |
| title_short | Mechanisms of Cancer-Associated Thrombosis: Role of Cancer-Derived
Exosomes |
| title_sort | mechanisms of cancer-associated thrombosis: role of cancer-derived
exosomes |
| url | http://hdl.handle.net/20.500.11937/95952 |