Kidney Beam - a cost-effective digital intervention to improve mental health.
Introduction: There is inequity in the provision of physical rehabilitation services for people living with chronic kidney disease (CKD). The Kidney BEAM trial evaluated the clinical value and cost effectiveness of a physical activity digital health intervention (DHI) in CKD. Methods: In a single...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
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Elsevier
2024
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| Online Access: | http://hdl.handle.net/20.500.11937/95801 |
| _version_ | 1848766049548238848 |
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| author | Greenwood, S. Briggs, J. Walklin, C. Mangahis, E. Young, H. Castle, Ellen Billany, R. Asgari, E. Bhandari, S. Bishop, N. Bramham, K. Burton, J. Campbell, J. Chilcot, J. Cooper, N. Deelchand, V, Graham-Brown, M. Haggis, L. Hamilton, A. Jesky, M. Kalra, P. Koufaki, P. McCafferty, K. Nixon, A. Noble, H. Saynor, Z. Taal, M. Tollitt, J. Wheeler, D. Wilkinson, T. Worboys, H. Macdonald, J. |
| author_facet | Greenwood, S. Briggs, J. Walklin, C. Mangahis, E. Young, H. Castle, Ellen Billany, R. Asgari, E. Bhandari, S. Bishop, N. Bramham, K. Burton, J. Campbell, J. Chilcot, J. Cooper, N. Deelchand, V, Graham-Brown, M. Haggis, L. Hamilton, A. Jesky, M. Kalra, P. Koufaki, P. McCafferty, K. Nixon, A. Noble, H. Saynor, Z. Taal, M. Tollitt, J. Wheeler, D. Wilkinson, T. Worboys, H. Macdonald, J. |
| author_sort | Greenwood, S. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Introduction: There is inequity in the provision of physical rehabilitation services for people living with
chronic kidney disease (CKD). The Kidney BEAM trial evaluated the clinical value and cost effectiveness of
a physical activity digital health intervention (DHI) in CKD.
Methods: In a single-blind, 11 center, randomized controlled trial, 340 adult participants with CKD were
randomly assigned to either the Kidney BEAM physical activity DHI or a waitlist control. This study
assessed the difference in the Kidney Disease Quality of Life Short Form 1.3 Mental Component Summary
(KDQoL-SF1.3 MCS) between intervention and control groups at 6-months, and cost-effectiveness of the
intervention.
Results: At 6-months, there was a significant difference in mean adjusted change in KDQoL MCS score
between Kidney BEAM and waitlist control (intention-to-treat adjusted mean: 5.9 [95% confidence interval,
CI: 4.4–7.5] arbitrary units [AU], P < 0.0001), and a 93% and 98% chance of the intervention being cost effective at a willingness-to-pay threshold of £20,000 and £30,000 per quality-adjusted life year gained.
Conclusion: The Kidney BEAM physical activity DHI is a clinically valuable and cost-effective means to
improve mental health-related quality of life (HRQoL) in people with CKD (trial registration no.
NCT04872933) |
| first_indexed | 2025-11-14T11:44:58Z |
| format | Journal Article |
| id | curtin-20.500.11937-95801 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:44:58Z |
| publishDate | 2024 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-958012025-01-28T01:59:10Z Kidney Beam - a cost-effective digital intervention to improve mental health. Greenwood, S. Briggs, J. Walklin, C. Mangahis, E. Young, H. Castle, Ellen Billany, R. Asgari, E. Bhandari, S. Bishop, N. Bramham, K. Burton, J. Campbell, J. Chilcot, J. Cooper, N. Deelchand, V, Graham-Brown, M. Haggis, L. Hamilton, A. Jesky, M. Kalra, P. Koufaki, P. McCafferty, K. Nixon, A. Noble, H. Saynor, Z. Taal, M. Tollitt, J. Wheeler, D. Wilkinson, T. Worboys, H. Macdonald, J. Introduction: There is inequity in the provision of physical rehabilitation services for people living with chronic kidney disease (CKD). The Kidney BEAM trial evaluated the clinical value and cost effectiveness of a physical activity digital health intervention (DHI) in CKD. Methods: In a single-blind, 11 center, randomized controlled trial, 340 adult participants with CKD were randomly assigned to either the Kidney BEAM physical activity DHI or a waitlist control. This study assessed the difference in the Kidney Disease Quality of Life Short Form 1.3 Mental Component Summary (KDQoL-SF1.3 MCS) between intervention and control groups at 6-months, and cost-effectiveness of the intervention. Results: At 6-months, there was a significant difference in mean adjusted change in KDQoL MCS score between Kidney BEAM and waitlist control (intention-to-treat adjusted mean: 5.9 [95% confidence interval, CI: 4.4–7.5] arbitrary units [AU], P < 0.0001), and a 93% and 98% chance of the intervention being cost effective at a willingness-to-pay threshold of £20,000 and £30,000 per quality-adjusted life year gained. Conclusion: The Kidney BEAM physical activity DHI is a clinically valuable and cost-effective means to improve mental health-related quality of life (HRQoL) in people with CKD (trial registration no. NCT04872933) 2024 Journal Article http://hdl.handle.net/20.500.11937/95801 10.1016/j.ekir.2024.08.030 http://creativecommons.org/licenses/by/4.0/ Elsevier fulltext |
| spellingShingle | Greenwood, S. Briggs, J. Walklin, C. Mangahis, E. Young, H. Castle, Ellen Billany, R. Asgari, E. Bhandari, S. Bishop, N. Bramham, K. Burton, J. Campbell, J. Chilcot, J. Cooper, N. Deelchand, V, Graham-Brown, M. Haggis, L. Hamilton, A. Jesky, M. Kalra, P. Koufaki, P. McCafferty, K. Nixon, A. Noble, H. Saynor, Z. Taal, M. Tollitt, J. Wheeler, D. Wilkinson, T. Worboys, H. Macdonald, J. Kidney Beam - a cost-effective digital intervention to improve mental health. |
| title | Kidney Beam - a cost-effective digital intervention to improve mental health. |
| title_full | Kidney Beam - a cost-effective digital intervention to improve mental health. |
| title_fullStr | Kidney Beam - a cost-effective digital intervention to improve mental health. |
| title_full_unstemmed | Kidney Beam - a cost-effective digital intervention to improve mental health. |
| title_short | Kidney Beam - a cost-effective digital intervention to improve mental health. |
| title_sort | kidney beam - a cost-effective digital intervention to improve mental health. |
| url | http://hdl.handle.net/20.500.11937/95801 |