Developing Next-Generation Genome Editing Tools
Genome editing is a revolutionary biotechnological field allowing scientists to modify DNA with precision. However, current technologies remain limited and there is a need to explore new genome editing techniques that may provide alternatives to the existing techniques, which is the focus of this th...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Published: |
Curtin University
2024
|
| Online Access: | http://hdl.handle.net/20.500.11937/95683 |
| _version_ | 1848766042236518400 |
|---|---|
| author | Gandadireja, Andrianto Prayogo |
| author_facet | Gandadireja, Andrianto Prayogo |
| author_sort | Gandadireja, Andrianto Prayogo |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Genome editing is a revolutionary biotechnological field allowing scientists to modify DNA with precision. However, current technologies remain limited and there is a need to explore new genome editing techniques that may provide alternatives to the existing techniques, which is the focus of this thesis. Here we proposed and explored three relatively new systems, namely, prokaryotic argonautes, next-generation adenine base editors, and mitochondrial RNA deaminases, which we have characterised and improved in this work. |
| first_indexed | 2025-11-14T11:44:51Z |
| format | Thesis |
| id | curtin-20.500.11937-95683 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:44:51Z |
| publishDate | 2024 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-956832024-08-12T02:39:19Z Developing Next-Generation Genome Editing Tools Gandadireja, Andrianto Prayogo Genome editing is a revolutionary biotechnological field allowing scientists to modify DNA with precision. However, current technologies remain limited and there is a need to explore new genome editing techniques that may provide alternatives to the existing techniques, which is the focus of this thesis. Here we proposed and explored three relatively new systems, namely, prokaryotic argonautes, next-generation adenine base editors, and mitochondrial RNA deaminases, which we have characterised and improved in this work. 2024 Thesis http://hdl.handle.net/20.500.11937/95683 Curtin University restricted |
| spellingShingle | Gandadireja, Andrianto Prayogo Developing Next-Generation Genome Editing Tools |
| title | Developing Next-Generation Genome Editing Tools |
| title_full | Developing Next-Generation Genome Editing Tools |
| title_fullStr | Developing Next-Generation Genome Editing Tools |
| title_full_unstemmed | Developing Next-Generation Genome Editing Tools |
| title_short | Developing Next-Generation Genome Editing Tools |
| title_sort | developing next-generation genome editing tools |
| url | http://hdl.handle.net/20.500.11937/95683 |