Towards Understanding the Role of Trisomy 21 in Down Syndrome Leukaemia

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Towards Understanding the Role of Trisomy 21 in Down Syndrome Leukaemia

Acute lymphoblastic leukaemia (ALL) is the most common paediatric cancer (25% of all cases). Children with Down syndrome (constitutive trisomy 21) are predisposed to ALL with inferior prognosis compared to other children. I established novel models of DS-ALL to dissect the role of trisomy 21 and ide...

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Bibliographic Details
Main Author:	Carey-Smith, Shannon Lee
Format:	Thesis
Published:	Curtin University 2024
Online Access:	http://hdl.handle.net/20.500.11937/95646

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