Molecular and Genetic Characterisation of Bacterial Cell-Cell Signalling

Many bacteria use chemical signalling molecules called AHLs to communicate with other bacteria to regulate various traits, in a phenomenon called quorum sensing. AHLs are synthesised by one protein-family called LuxI, and the molecules vary between systems. This thesis describes two different quorum...

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Bibliographic Details
Main Author: Bastholm, Tahlia
Format: Thesis
Published: Curtin University 2023
Online Access:http://hdl.handle.net/20.500.11937/95434
Description
Summary:Many bacteria use chemical signalling molecules called AHLs to communicate with other bacteria to regulate various traits, in a phenomenon called quorum sensing. AHLs are synthesised by one protein-family called LuxI, and the molecules vary between systems. This thesis describes two different quorum sensing systems in the plant associated Mesorhizobium. One uniquely requires two proteins – LuxI and a crotonase – to synthesise unusual AHLs. The second system epigenetically regulates the movement of DNA between bacterial cells.