Bacteriophage therapy for multi-drug resistant Staphylococcus aureus infections within the airways
This thesis supports the potential of phages in treating respiratory infections caused by Staphylococcus aureus bacteria, including MRSA. Phages Koomba kaat 1 and Biyabeda mokiny 1 demonstrated broad ranges of activity and remained stable when aerosolised. Genomic characterisation ensured contaminan...
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| Format: | Thesis |
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Curtin University
2023
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| Online Access: | http://hdl.handle.net/20.500.11937/95175 |
| _version_ | 1848765976981536768 |
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| author | Iszatt, Joshua James |
| author_facet | Iszatt, Joshua James |
| author_sort | Iszatt, Joshua James |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | This thesis supports the potential of phages in treating respiratory infections caused by Staphylococcus aureus bacteria, including MRSA. Phages Koomba kaat 1 and Biyabeda mokiny 1 demonstrated broad ranges of activity and remained stable when aerosolised. Genomic characterisation ensured contaminant free samples whilst in vitro and in vivo models validated their safety. Collectively, this study provided crucial preclinical insight, supporting their use for clinical trials to treat S. aureus respiratory infections. |
| first_indexed | 2025-11-14T11:43:49Z |
| format | Thesis |
| id | curtin-20.500.11937-95175 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:43:49Z |
| publishDate | 2023 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-951752024-05-28T00:54:54Z Bacteriophage therapy for multi-drug resistant Staphylococcus aureus infections within the airways Iszatt, Joshua James This thesis supports the potential of phages in treating respiratory infections caused by Staphylococcus aureus bacteria, including MRSA. Phages Koomba kaat 1 and Biyabeda mokiny 1 demonstrated broad ranges of activity and remained stable when aerosolised. Genomic characterisation ensured contaminant free samples whilst in vitro and in vivo models validated their safety. Collectively, this study provided crucial preclinical insight, supporting their use for clinical trials to treat S. aureus respiratory infections. 2023 Thesis http://hdl.handle.net/20.500.11937/95175 Curtin University fulltext |
| spellingShingle | Iszatt, Joshua James Bacteriophage therapy for multi-drug resistant Staphylococcus aureus infections within the airways |
| title | Bacteriophage therapy for multi-drug resistant Staphylococcus aureus infections within the airways |
| title_full | Bacteriophage therapy for multi-drug resistant Staphylococcus aureus infections within the airways |
| title_fullStr | Bacteriophage therapy for multi-drug resistant Staphylococcus aureus infections within the airways |
| title_full_unstemmed | Bacteriophage therapy for multi-drug resistant Staphylococcus aureus infections within the airways |
| title_short | Bacteriophage therapy for multi-drug resistant Staphylococcus aureus infections within the airways |
| title_sort | bacteriophage therapy for multi-drug resistant staphylococcus aureus infections within the airways |
| url | http://hdl.handle.net/20.500.11937/95175 |