N1-P2 event-related potentials and perceived intensity are associated: The effects of a weak pre-stimulus and attentional load on processing of a subsequent intense stimulus
A weak stimulus presented immediately before a more intense one reduces both the N1-P2 cortical response and the perceived intensity of the intense stimulus. The former effect is referred to as cortical prepulse inhibition (PPI), the latter as prepulse inhibition of perceived stimulus intensity (PPI...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2023
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| Online Access: | http://purl.org/au-research/grants/arc/DP180100394 http://hdl.handle.net/20.500.11937/94729 |
| _version_ | 1848765907326730240 |
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| author | Favero, J.D. Luck, Camilla Lipp, Ottmar Nguyen, A.T. Marinovic, Welber |
| author_facet | Favero, J.D. Luck, Camilla Lipp, Ottmar Nguyen, A.T. Marinovic, Welber |
| author_sort | Favero, J.D. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | A weak stimulus presented immediately before a more intense one reduces both the N1-P2 cortical response and the perceived intensity of the intense stimulus. The former effect is referred to as cortical prepulse inhibition (PPI), the latter as prepulse inhibition of perceived stimulus intensity (PPIPSI). Both phenomena are used to study sensory gating in clinical and non-clinical populations, however little is known about their relationship. Here, we investigated 1) the possibility that cortical PPI and PPIPSI are associated, and 2) how they are affected by attentional load. Participants were tasked with comparing the intensity of an electric pulse presented alone versus one preceded 200 ms by a weaker electric prepulse (Experiment 1), or an acoustic pulse presented alone with one preceded 170 ms by a weaker acoustic prepulse (Experiment 2). A counting task (easy vs. hard) manipulating attentional load was included in Experiment 2. In both experiments, we observed a relationship between N1-P2 amplitude and perceived intensity, where greater cortical PPI was associated with a higher probability of perceiving the ‘pulse with prepulse’ as less intense. Moreover, higher attentional load decreased observations of PPIPSI but had no effect on N1-P2 amplitude. Based on the findings we propose that PPIPSI partially relies on the allocation of attentional resources towards monitoring cortical channels that process stimulus intensity characteristics such as the N1-P2 complex. |
| first_indexed | 2025-11-14T11:42:42Z |
| format | Journal Article |
| id | curtin-20.500.11937-94729 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | eng |
| last_indexed | 2025-11-14T11:42:42Z |
| publishDate | 2023 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-947292024-05-07T06:37:16Z N1-P2 event-related potentials and perceived intensity are associated: The effects of a weak pre-stimulus and attentional load on processing of a subsequent intense stimulus Favero, J.D. Luck, Camilla Lipp, Ottmar Nguyen, A.T. Marinovic, Welber Attention Inhibition N1-P2 complex PPIPSI Perceived intensity Perception Prepulse Humans Reflex, Startle Acoustic Stimulation Evoked Potentials Prepulse Inhibition Attention Humans Acoustic Stimulation Attention Evoked Potentials Reflex, Startle Prepulse Inhibition A weak stimulus presented immediately before a more intense one reduces both the N1-P2 cortical response and the perceived intensity of the intense stimulus. The former effect is referred to as cortical prepulse inhibition (PPI), the latter as prepulse inhibition of perceived stimulus intensity (PPIPSI). Both phenomena are used to study sensory gating in clinical and non-clinical populations, however little is known about their relationship. Here, we investigated 1) the possibility that cortical PPI and PPIPSI are associated, and 2) how they are affected by attentional load. Participants were tasked with comparing the intensity of an electric pulse presented alone versus one preceded 200 ms by a weaker electric prepulse (Experiment 1), or an acoustic pulse presented alone with one preceded 170 ms by a weaker acoustic prepulse (Experiment 2). A counting task (easy vs. hard) manipulating attentional load was included in Experiment 2. In both experiments, we observed a relationship between N1-P2 amplitude and perceived intensity, where greater cortical PPI was associated with a higher probability of perceiving the ‘pulse with prepulse’ as less intense. Moreover, higher attentional load decreased observations of PPIPSI but had no effect on N1-P2 amplitude. Based on the findings we propose that PPIPSI partially relies on the allocation of attentional resources towards monitoring cortical channels that process stimulus intensity characteristics such as the N1-P2 complex. 2023 Journal Article http://hdl.handle.net/20.500.11937/94729 10.1016/j.biopsycho.2023.108711 eng http://purl.org/au-research/grants/arc/DP180100394 http://creativecommons.org/licenses/by/4.0/ fulltext |
| spellingShingle | Attention Inhibition N1-P2 complex PPIPSI Perceived intensity Perception Prepulse Humans Reflex, Startle Acoustic Stimulation Evoked Potentials Prepulse Inhibition Attention Humans Acoustic Stimulation Attention Evoked Potentials Reflex, Startle Prepulse Inhibition Favero, J.D. Luck, Camilla Lipp, Ottmar Nguyen, A.T. Marinovic, Welber N1-P2 event-related potentials and perceived intensity are associated: The effects of a weak pre-stimulus and attentional load on processing of a subsequent intense stimulus |
| title | N1-P2 event-related potentials and perceived intensity are associated: The effects of a weak pre-stimulus and attentional load on processing of a subsequent intense stimulus |
| title_full | N1-P2 event-related potentials and perceived intensity are associated: The effects of a weak pre-stimulus and attentional load on processing of a subsequent intense stimulus |
| title_fullStr | N1-P2 event-related potentials and perceived intensity are associated: The effects of a weak pre-stimulus and attentional load on processing of a subsequent intense stimulus |
| title_full_unstemmed | N1-P2 event-related potentials and perceived intensity are associated: The effects of a weak pre-stimulus and attentional load on processing of a subsequent intense stimulus |
| title_short | N1-P2 event-related potentials and perceived intensity are associated: The effects of a weak pre-stimulus and attentional load on processing of a subsequent intense stimulus |
| title_sort | n1-p2 event-related potentials and perceived intensity are associated: the effects of a weak pre-stimulus and attentional load on processing of a subsequent intense stimulus |
| topic | Attention Inhibition N1-P2 complex PPIPSI Perceived intensity Perception Prepulse Humans Reflex, Startle Acoustic Stimulation Evoked Potentials Prepulse Inhibition Attention Humans Acoustic Stimulation Attention Evoked Potentials Reflex, Startle Prepulse Inhibition |
| url | http://purl.org/au-research/grants/arc/DP180100394 http://hdl.handle.net/20.500.11937/94729 |