The Effect of Naturally Occurring Osmolytes and Organic Solvents on the Structure and Folding of Intrinsically Disordered Proteins
The thesis looks into amylin, a type of protein linked to type-2 diabetes. Using computer simulations, the study examines the individual forms of amylin in both humans and rats. The research validates the methods and looks at how different chemicals HFIP, TMAO and urea affects amylin structure. The...
| Main Author: | |
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| Format: | Thesis |
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Curtin University
2023
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| Online Access: | http://hdl.handle.net/20.500.11937/94618 |
| _version_ | 1848765891162931200 |
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| author | Moore, Sandra Jayne |
| author_facet | Moore, Sandra Jayne |
| author_sort | Moore, Sandra Jayne |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The thesis looks into amylin, a type of protein linked to type-2 diabetes. Using computer simulations, the study examines the individual forms of amylin in both humans and rats. The research validates the methods and looks at how different chemicals HFIP, TMAO and urea affects amylin structure. The results provide a better understanding of amylin's basic form, how it changes in different conditions. |
| first_indexed | 2025-11-14T11:42:27Z |
| format | Thesis |
| id | curtin-20.500.11937-94618 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:42:27Z |
| publishDate | 2023 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-946182024-03-28T01:05:25Z The Effect of Naturally Occurring Osmolytes and Organic Solvents on the Structure and Folding of Intrinsically Disordered Proteins Moore, Sandra Jayne The thesis looks into amylin, a type of protein linked to type-2 diabetes. Using computer simulations, the study examines the individual forms of amylin in both humans and rats. The research validates the methods and looks at how different chemicals HFIP, TMAO and urea affects amylin structure. The results provide a better understanding of amylin's basic form, how it changes in different conditions. 2023 Thesis http://hdl.handle.net/20.500.11937/94618 Curtin University restricted |
| spellingShingle | Moore, Sandra Jayne The Effect of Naturally Occurring Osmolytes and Organic Solvents on the Structure and Folding of Intrinsically Disordered Proteins |
| title | The Effect of Naturally Occurring Osmolytes
and Organic Solvents on the Structure and
Folding of Intrinsically Disordered Proteins |
| title_full | The Effect of Naturally Occurring Osmolytes
and Organic Solvents on the Structure and
Folding of Intrinsically Disordered Proteins |
| title_fullStr | The Effect of Naturally Occurring Osmolytes
and Organic Solvents on the Structure and
Folding of Intrinsically Disordered Proteins |
| title_full_unstemmed | The Effect of Naturally Occurring Osmolytes
and Organic Solvents on the Structure and
Folding of Intrinsically Disordered Proteins |
| title_short | The Effect of Naturally Occurring Osmolytes
and Organic Solvents on the Structure and
Folding of Intrinsically Disordered Proteins |
| title_sort | effect of naturally occurring osmolytes
and organic solvents on the structure and
folding of intrinsically disordered proteins |
| url | http://hdl.handle.net/20.500.11937/94618 |