Vitamin D supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials
Vitamin D is anticipated to have many extra-skeletal health benefits. We questioned whether supplementation with the vitamin influenced body weight and composition. A systematic review and meta-analysis was conducted on high-quality, randomized controlled trials (RCTs) that had supplemented vitamin...
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| Format: | Journal Article |
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Wiley-Blackwell Publishing Ltd.
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/9440 |
| _version_ | 1848745950590271488 |
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| author | Pathak, K. Soares, Mario Calton, Emily Zhao, Yun Hallett, Jonathan |
| author_facet | Pathak, K. Soares, Mario Calton, Emily Zhao, Yun Hallett, Jonathan |
| author_sort | Pathak, K. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Vitamin D is anticipated to have many extra-skeletal health benefits. We questioned whether supplementation with the vitamin influenced body weight and composition. A systematic review and meta-analysis was conducted on high-quality, randomized controlled trials (RCTs) that had supplemented vitamin D without imposing any caloric restriction. Eighteen trials reporting either body weight, body mass index (BMI), fat mass (FM), percentage fat mass (%FM) or lean body mass (LBM) met our criteria. Twelve studies provided the required data for the meta-analysis. Vitamin D supplementation did not influence the standardized mean difference (SMD) for body weight, FM, %FM or LBM. A small but non-significant decrease in BMI (SMD = -0.097, 95% confidence interval: [-0.210, 0.016], P = 0.092) was observed. Meta-regression confirmed that neither the absolute vitamin D status achieved nor its change from baseline influenced the SMD of any obesity measure. However, increasing age of the subjects predicted a shift in the SMD for FM towards the placebo treatment, whereas a greater percentage of women in these studies favoured a decrease in FM following vitamin D. Vitamin D supplementation did not decrease measures of adiposity in the absence of caloric restriction. A potential confounding by age and gender was encountered. |
| first_indexed | 2025-11-14T06:25:30Z |
| format | Journal Article |
| id | curtin-20.500.11937-9440 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T06:25:30Z |
| publishDate | 2014 |
| publisher | Wiley-Blackwell Publishing Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-94402017-10-02T02:28:09Z Vitamin D supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials Pathak, K. Soares, Mario Calton, Emily Zhao, Yun Hallett, Jonathan supplementation Obesity vitamin D Vitamin D is anticipated to have many extra-skeletal health benefits. We questioned whether supplementation with the vitamin influenced body weight and composition. A systematic review and meta-analysis was conducted on high-quality, randomized controlled trials (RCTs) that had supplemented vitamin D without imposing any caloric restriction. Eighteen trials reporting either body weight, body mass index (BMI), fat mass (FM), percentage fat mass (%FM) or lean body mass (LBM) met our criteria. Twelve studies provided the required data for the meta-analysis. Vitamin D supplementation did not influence the standardized mean difference (SMD) for body weight, FM, %FM or LBM. A small but non-significant decrease in BMI (SMD = -0.097, 95% confidence interval: [-0.210, 0.016], P = 0.092) was observed. Meta-regression confirmed that neither the absolute vitamin D status achieved nor its change from baseline influenced the SMD of any obesity measure. However, increasing age of the subjects predicted a shift in the SMD for FM towards the placebo treatment, whereas a greater percentage of women in these studies favoured a decrease in FM following vitamin D. Vitamin D supplementation did not decrease measures of adiposity in the absence of caloric restriction. A potential confounding by age and gender was encountered. 2014 Journal Article http://hdl.handle.net/20.500.11937/9440 10.1111/obr.12162 Wiley-Blackwell Publishing Ltd. restricted |
| spellingShingle | supplementation Obesity vitamin D Pathak, K. Soares, Mario Calton, Emily Zhao, Yun Hallett, Jonathan Vitamin D supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials |
| title | Vitamin D supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials |
| title_full | Vitamin D supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials |
| title_fullStr | Vitamin D supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials |
| title_full_unstemmed | Vitamin D supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials |
| title_short | Vitamin D supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials |
| title_sort | vitamin d supplementation and body weight status: a systematic review and meta-analysis of randomized controlled trials |
| topic | supplementation Obesity vitamin D |
| url | http://hdl.handle.net/20.500.11937/9440 |