Comparative Study of Eclipse and RayStation Multi-Criteria Optimization-Based Prostate Radiotherapy Treatment Planning Quality
Multi-criteria optimization (MCO) function has been available on commercial radiotherapy (RT) treatment planning systems to improve plan quality; however, no study has compared Eclipse and RayStation MCO functions for prostate RT planning. The purpose of this study was to compare prostate RT MCO pla...
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| Format: | Journal Article |
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MDPI
2024
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| Online Access: | http://hdl.handle.net/20.500.11937/94393 |
| _version_ | 1848765867078189056 |
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| author | Wong, John YK Leung, Vincent WS Hung, Rico HM Ng, Curtise |
| author_facet | Wong, John YK Leung, Vincent WS Hung, Rico HM Ng, Curtise |
| author_sort | Wong, John YK |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Multi-criteria optimization (MCO) function has been available on commercial radiotherapy (RT) treatment planning systems to improve plan quality; however, no study has compared Eclipse and RayStation MCO functions for prostate RT planning. The purpose of this study was to compare prostate RT MCO plan qualities in terms of discrepancies between Pareto optimal and final deliverable plans, and dosimetric impact of final deliverable plans. In total, 25 computed tomography datasets of prostate cancer patients were used for Eclipse (version 16.1) and RayStation (version 12A) MCO-based plannings with doses received by 98% of planning target volume having 76 Gy prescription (PTV76 D98%) and 50% of rectum (rectum D50%) selected as trade-off criteria. Pareto optimal and final deliverable plan discrepancies were determined based on PTV76 D98% and rectum D50% percentage differences. Their final deliverable plans were compared in terms of doses received by PTV76 and other structures including rectum, and PTV76 homogeneity index (HI) and conformity index (CI), using a t-test. Both systems showed discrepancies between Pareto optimal and final deliverable plans (Eclipse: −0.89% (PTV76 D98%) and −2.49% (Rectum D50%); RayStation: 3.56% (PTV76 D98%) and −1.96% (Rectum D50%)). Statistically significantly different average values of PTV76 D98%, HI and CI, and mean dose received by rectum (Eclipse: 76.07 Gy, 0.06, 1.05 and 39.36 Gy; RayStation: 70.43 Gy, 0.11, 0.87 and 51.65 Gy) are noted, respectively (p < 0.001). Eclipse MCO-based prostate RT plan quality appears better than that of RayStation. |
| first_indexed | 2025-11-14T11:42:04Z |
| format | Journal Article |
| id | curtin-20.500.11937-94393 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:42:04Z |
| publishDate | 2024 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-943932024-04-04T08:00:30Z Comparative Study of Eclipse and RayStation Multi-Criteria Optimization-Based Prostate Radiotherapy Treatment Planning Quality Wong, John YK Leung, Vincent WS Hung, Rico HM Ng, Curtise Cancer Gleason Score Organs at Risk Pareto Front Pareto Surface Prostate-Specific Antigen Radiation Therapy Target Volume Toxicity Trade-off Multi-criteria optimization (MCO) function has been available on commercial radiotherapy (RT) treatment planning systems to improve plan quality; however, no study has compared Eclipse and RayStation MCO functions for prostate RT planning. The purpose of this study was to compare prostate RT MCO plan qualities in terms of discrepancies between Pareto optimal and final deliverable plans, and dosimetric impact of final deliverable plans. In total, 25 computed tomography datasets of prostate cancer patients were used for Eclipse (version 16.1) and RayStation (version 12A) MCO-based plannings with doses received by 98% of planning target volume having 76 Gy prescription (PTV76 D98%) and 50% of rectum (rectum D50%) selected as trade-off criteria. Pareto optimal and final deliverable plan discrepancies were determined based on PTV76 D98% and rectum D50% percentage differences. Their final deliverable plans were compared in terms of doses received by PTV76 and other structures including rectum, and PTV76 homogeneity index (HI) and conformity index (CI), using a t-test. Both systems showed discrepancies between Pareto optimal and final deliverable plans (Eclipse: −0.89% (PTV76 D98%) and −2.49% (Rectum D50%); RayStation: 3.56% (PTV76 D98%) and −1.96% (Rectum D50%)). Statistically significantly different average values of PTV76 D98%, HI and CI, and mean dose received by rectum (Eclipse: 76.07 Gy, 0.06, 1.05 and 39.36 Gy; RayStation: 70.43 Gy, 0.11, 0.87 and 51.65 Gy) are noted, respectively (p < 0.001). Eclipse MCO-based prostate RT plan quality appears better than that of RayStation. 2024 Journal Article http://hdl.handle.net/20.500.11937/94393 10.3390/diagnostics14050465 http://creativecommons.org/licenses/by/4.0/ MDPI fulltext |
| spellingShingle | Cancer Gleason Score Organs at Risk Pareto Front Pareto Surface Prostate-Specific Antigen Radiation Therapy Target Volume Toxicity Trade-off Wong, John YK Leung, Vincent WS Hung, Rico HM Ng, Curtise Comparative Study of Eclipse and RayStation Multi-Criteria Optimization-Based Prostate Radiotherapy Treatment Planning Quality |
| title | Comparative Study of Eclipse and RayStation Multi-Criteria Optimization-Based Prostate Radiotherapy Treatment Planning Quality |
| title_full | Comparative Study of Eclipse and RayStation Multi-Criteria Optimization-Based Prostate Radiotherapy Treatment Planning Quality |
| title_fullStr | Comparative Study of Eclipse and RayStation Multi-Criteria Optimization-Based Prostate Radiotherapy Treatment Planning Quality |
| title_full_unstemmed | Comparative Study of Eclipse and RayStation Multi-Criteria Optimization-Based Prostate Radiotherapy Treatment Planning Quality |
| title_short | Comparative Study of Eclipse and RayStation Multi-Criteria Optimization-Based Prostate Radiotherapy Treatment Planning Quality |
| title_sort | comparative study of eclipse and raystation multi-criteria optimization-based prostate radiotherapy treatment planning quality |
| topic | Cancer Gleason Score Organs at Risk Pareto Front Pareto Surface Prostate-Specific Antigen Radiation Therapy Target Volume Toxicity Trade-off |
| url | http://hdl.handle.net/20.500.11937/94393 |