Escalation of care in children at high risk of clinical deterioration in a tertiary care children’s hospital using the Bedside Pediatric Early Warning System
Background: Escalation and de-escalation are a routine part of high-quality care that should be matched with clinical needs. The aim of this study was to describe escalation of care in relation to the occurrence and timing of Pediatric Intensive Care Unit (PICU) admission in a cohort of pediatric in...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
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BMC
2022
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| Online Access: | http://hdl.handle.net/20.500.11937/94026 |
| _version_ | 1848765832472035328 |
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| author | Gawronski, O. Latour, Jos Cecchetti, C. Iula, A. Ravà, L. Ciofi degli Atti, M.L. Dall’Oglio, I. Tiozzo, E. Raponi, M. Parshuram, C.S. |
| author_facet | Gawronski, O. Latour, Jos Cecchetti, C. Iula, A. Ravà, L. Ciofi degli Atti, M.L. Dall’Oglio, I. Tiozzo, E. Raponi, M. Parshuram, C.S. |
| author_sort | Gawronski, O. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: Escalation and de-escalation are a routine part of high-quality care that should be matched with clinical needs. The aim of this study was to describe escalation of care in relation to the occurrence and timing of Pediatric Intensive Care Unit (PICU) admission in a cohort of pediatric inpatients with acute worsening of their clinical condition. Methods: A monocentric, observational cohort study was performed from January to December 2018. Eligible patients were children: 1) admitted to one of the inpatient wards other than ICU; 2) under the age of 18 years at the time of admission; 3) with two or more Bedside-Paediatric-Early-Warning-System (BedsidePEWS) scores ≥ 7 recorded at a distance of at least one hour and for a period of 4 h during admission. The main outcome -the 24-h disposition – was defined as admission to PICU within 24-h of enrolment or staying in the inpatient ward. Escalation of care was measured using an eight-point scale—the Escalation Index (EI), developed by the authors. The EI was calculated every 6 h, starting from the moment the patient was considered eligible. Analyses used multivariate quantile and logistic regression models. Results: The 228 episodes included 574 EI calculated scores. The 24-h disposition was the ward in 129 (57%) and the PICU in 99 (43%) episodes. Patients who were admitted to PICU within 24-h had higher top EI scores [median (IQR) 6 (5–7) vs 4 (3–5), p < 0.001]; higher initial BedsidePEWS scores [median (IQR) 10(8–13) vs. 9 (8–11), p = 0.02], were less likely to have a chronic disease [n = 62 (63%) vs. n = 127 (98%), p < 0.0001], and were rated by physicians as being at a higher risk of having a cardiac arrest (p = 0.01) than patients remaining on the ward. The EI increased over 24 h before urgent admission to PICU or cardiac arrest by 0.53 every 6-h interval (CI 0.37–0.70, p < 0.001), while it decreased by 0.25 every 6-h interval (CI -0.36–0.15, p < 0.001) in patients who stayed on the wards. Conclusion: Escalation of care was related to temporal changes in severity of illness, patient background and environmental factors. The EI index can improve responses to evolving critical illness. |
| first_indexed | 2025-11-14T11:41:31Z |
| format | Journal Article |
| id | curtin-20.500.11937-94026 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T11:41:31Z |
| publishDate | 2022 |
| publisher | BMC |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-940262024-01-24T05:58:10Z Escalation of care in children at high risk of clinical deterioration in a tertiary care children’s hospital using the Bedside Pediatric Early Warning System Gawronski, O. Latour, Jos Cecchetti, C. Iula, A. Ravà, L. Ciofi degli Atti, M.L. Dall’Oglio, I. Tiozzo, E. Raponi, M. Parshuram, C.S. Science & Technology Life Sciences & Biomedicine Pediatrics Escalation of care Pediatric Track and trigger tool BedsidePEWS PEWS Intensive care Urgent admission TRACK BedsidePEWS Escalation of care Intensive care PEWS Pediatric Track and trigger tool Urgent admission Adolescent Child Clinical Deterioration Heart Arrest Hospitals Humans Retrospective Studies Tertiary Healthcare Humans Heart Arrest Retrospective Studies Adolescent Child Hospitals Tertiary Healthcare Clinical Deterioration Background: Escalation and de-escalation are a routine part of high-quality care that should be matched with clinical needs. The aim of this study was to describe escalation of care in relation to the occurrence and timing of Pediatric Intensive Care Unit (PICU) admission in a cohort of pediatric inpatients with acute worsening of their clinical condition. Methods: A monocentric, observational cohort study was performed from January to December 2018. Eligible patients were children: 1) admitted to one of the inpatient wards other than ICU; 2) under the age of 18 years at the time of admission; 3) with two or more Bedside-Paediatric-Early-Warning-System (BedsidePEWS) scores ≥ 7 recorded at a distance of at least one hour and for a period of 4 h during admission. The main outcome -the 24-h disposition – was defined as admission to PICU within 24-h of enrolment or staying in the inpatient ward. Escalation of care was measured using an eight-point scale—the Escalation Index (EI), developed by the authors. The EI was calculated every 6 h, starting from the moment the patient was considered eligible. Analyses used multivariate quantile and logistic regression models. Results: The 228 episodes included 574 EI calculated scores. The 24-h disposition was the ward in 129 (57%) and the PICU in 99 (43%) episodes. Patients who were admitted to PICU within 24-h had higher top EI scores [median (IQR) 6 (5–7) vs 4 (3–5), p < 0.001]; higher initial BedsidePEWS scores [median (IQR) 10(8–13) vs. 9 (8–11), p = 0.02], were less likely to have a chronic disease [n = 62 (63%) vs. n = 127 (98%), p < 0.0001], and were rated by physicians as being at a higher risk of having a cardiac arrest (p = 0.01) than patients remaining on the ward. The EI increased over 24 h before urgent admission to PICU or cardiac arrest by 0.53 every 6-h interval (CI 0.37–0.70, p < 0.001), while it decreased by 0.25 every 6-h interval (CI -0.36–0.15, p < 0.001) in patients who stayed on the wards. Conclusion: Escalation of care was related to temporal changes in severity of illness, patient background and environmental factors. The EI index can improve responses to evolving critical illness. 2022 Journal Article http://hdl.handle.net/20.500.11937/94026 10.1186/s12887-022-03555-0 English http://creativecommons.org/licenses/by/4.0/ BMC fulltext |
| spellingShingle | Science & Technology Life Sciences & Biomedicine Pediatrics Escalation of care Pediatric Track and trigger tool BedsidePEWS PEWS Intensive care Urgent admission TRACK BedsidePEWS Escalation of care Intensive care PEWS Pediatric Track and trigger tool Urgent admission Adolescent Child Clinical Deterioration Heart Arrest Hospitals Humans Retrospective Studies Tertiary Healthcare Humans Heart Arrest Retrospective Studies Adolescent Child Hospitals Tertiary Healthcare Clinical Deterioration Gawronski, O. Latour, Jos Cecchetti, C. Iula, A. Ravà, L. Ciofi degli Atti, M.L. Dall’Oglio, I. Tiozzo, E. Raponi, M. Parshuram, C.S. Escalation of care in children at high risk of clinical deterioration in a tertiary care children’s hospital using the Bedside Pediatric Early Warning System |
| title | Escalation of care in children at high risk of clinical deterioration in a tertiary care children’s hospital using the Bedside Pediatric Early Warning System |
| title_full | Escalation of care in children at high risk of clinical deterioration in a tertiary care children’s hospital using the Bedside Pediatric Early Warning System |
| title_fullStr | Escalation of care in children at high risk of clinical deterioration in a tertiary care children’s hospital using the Bedside Pediatric Early Warning System |
| title_full_unstemmed | Escalation of care in children at high risk of clinical deterioration in a tertiary care children’s hospital using the Bedside Pediatric Early Warning System |
| title_short | Escalation of care in children at high risk of clinical deterioration in a tertiary care children’s hospital using the Bedside Pediatric Early Warning System |
| title_sort | escalation of care in children at high risk of clinical deterioration in a tertiary care children’s hospital using the bedside pediatric early warning system |
| topic | Science & Technology Life Sciences & Biomedicine Pediatrics Escalation of care Pediatric Track and trigger tool BedsidePEWS PEWS Intensive care Urgent admission TRACK BedsidePEWS Escalation of care Intensive care PEWS Pediatric Track and trigger tool Urgent admission Adolescent Child Clinical Deterioration Heart Arrest Hospitals Humans Retrospective Studies Tertiary Healthcare Humans Heart Arrest Retrospective Studies Adolescent Child Hospitals Tertiary Healthcare Clinical Deterioration |
| url | http://hdl.handle.net/20.500.11937/94026 |