Understanding the Relationship between Iron and Lipid Metabolism in Non-alcoholic Fatty Liver Disease
This research shows that in the absence of steatosis short term iron exposure appears to improve mitochondrial function and decrease mitochondrial fatty acid breakdown. In contrast, in the presence of hepatic steatosis, iron increased peroxisomal fatty acid breakdown. Importantly, iron decreased the...
| Main Author: | |
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| Format: | Thesis |
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Curtin University
2022
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| Online Access: | http://hdl.handle.net/20.500.11937/93623 |
| _version_ | 1848765757032235008 |
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| author | Singh, Abhishek Kumar |
| author_facet | Singh, Abhishek Kumar |
| author_sort | Singh, Abhishek Kumar |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | This research shows that in the absence of steatosis short term iron exposure appears to improve mitochondrial function and decrease mitochondrial fatty acid breakdown. In contrast, in the presence of hepatic steatosis, iron increased peroxisomal fatty acid breakdown. Importantly, iron decreased the number of cholesterol crystals present in fatty liver. These results suggest iron loading in steatosis may act to reduce liver damage in non-alcoholic fatty liver disease. |
| first_indexed | 2025-11-14T11:40:19Z |
| format | Thesis |
| id | curtin-20.500.11937-93623 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:40:19Z |
| publishDate | 2022 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-936232023-10-26T01:01:03Z Understanding the Relationship between Iron and Lipid Metabolism in Non-alcoholic Fatty Liver Disease Singh, Abhishek Kumar This research shows that in the absence of steatosis short term iron exposure appears to improve mitochondrial function and decrease mitochondrial fatty acid breakdown. In contrast, in the presence of hepatic steatosis, iron increased peroxisomal fatty acid breakdown. Importantly, iron decreased the number of cholesterol crystals present in fatty liver. These results suggest iron loading in steatosis may act to reduce liver damage in non-alcoholic fatty liver disease. 2022 Thesis http://hdl.handle.net/20.500.11937/93623 Curtin University fulltext |
| spellingShingle | Singh, Abhishek Kumar Understanding the Relationship between Iron and Lipid Metabolism in Non-alcoholic Fatty Liver Disease |
| title | Understanding the Relationship between Iron and Lipid Metabolism in
Non-alcoholic Fatty Liver Disease |
| title_full | Understanding the Relationship between Iron and Lipid Metabolism in
Non-alcoholic Fatty Liver Disease |
| title_fullStr | Understanding the Relationship between Iron and Lipid Metabolism in
Non-alcoholic Fatty Liver Disease |
| title_full_unstemmed | Understanding the Relationship between Iron and Lipid Metabolism in
Non-alcoholic Fatty Liver Disease |
| title_short | Understanding the Relationship between Iron and Lipid Metabolism in
Non-alcoholic Fatty Liver Disease |
| title_sort | understanding the relationship between iron and lipid metabolism in
non-alcoholic fatty liver disease |
| url | http://hdl.handle.net/20.500.11937/93623 |