Gestational age as a predictor for subsequent preterm birth in New South Wales, Australia

Background: There is no validated evidence base on predictive ability and absolute risk of preterm birth by gestational age of the previous pregnancy. Methods: We conducted a retrospective cohort study of mothers who gave birth to their first two children in New South Wales, 1994–2016 (N = 517,558 m...

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Main Authors: Pereira, Gavin, Regan, Annette, Wong, Kingsley, Tessema, Gizachew
Format: Journal Article
Language:English
Published: BMC 2021
Subjects:
Online Access:http://purl.org/au-research/grants/nhmrc/1099655
http://hdl.handle.net/20.500.11937/93227
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author Pereira, Gavin
Regan, Annette
Wong, Kingsley
Tessema, Gizachew
author_facet Pereira, Gavin
Regan, Annette
Wong, Kingsley
Tessema, Gizachew
author_sort Pereira, Gavin
building Curtin Institutional Repository
collection Online Access
description Background: There is no validated evidence base on predictive ability and absolute risk of preterm birth by gestational age of the previous pregnancy. Methods: We conducted a retrospective cohort study of mothers who gave birth to their first two children in New South Wales, 1994–2016 (N = 517,558 mothers). For each week of final gestational age of the first birth, we calculated relative and absolute risks of subsequent preterm birth. Results: For mothers whose first birth had a gestational age of 22 to 30 weeks the absolute risks of clinically significant preterm second birth (before 28, 32, and 34 weeks) were all less than 14%. For all gestational ages of the first child the median gestational ages of the second child were all at least 38 weeks. Sensitivity and positive predictive values were all below 30%. Conclusion: Previous gestational age alone is a poor predictor of subsequent risk of preterm birth.
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spelling curtin-20.500.11937-932272023-10-09T03:26:49Z Gestational age as a predictor for subsequent preterm birth in New South Wales, Australia Pereira, Gavin Regan, Annette Wong, Kingsley Tessema, Gizachew Science & Technology Life Sciences & Biomedicine Obstetrics & Gynecology Premature birth Gestational age Recurrence Predictive value of tests Sensitivity and specificity RECURRENCE RISK HEALTH Gestational age Predictive value of tests Premature birth Recurrence Sensitivity and specificity Adult Australia Birth Order Female Gestational Age Gravidity Humans Infant, Newborn New South Wales Parity Pregnancy Premature Birth Retrospective Studies Risk Factors Young Adult Humans Premature Birth Risk Factors Retrospective Studies Birth Order Gravidity Parity Gestational Age Pregnancy Adult Infant, Newborn Australia New South Wales Female Young Adult Background: There is no validated evidence base on predictive ability and absolute risk of preterm birth by gestational age of the previous pregnancy. Methods: We conducted a retrospective cohort study of mothers who gave birth to their first two children in New South Wales, 1994–2016 (N = 517,558 mothers). For each week of final gestational age of the first birth, we calculated relative and absolute risks of subsequent preterm birth. Results: For mothers whose first birth had a gestational age of 22 to 30 weeks the absolute risks of clinically significant preterm second birth (before 28, 32, and 34 weeks) were all less than 14%. For all gestational ages of the first child the median gestational ages of the second child were all at least 38 weeks. Sensitivity and positive predictive values were all below 30%. Conclusion: Previous gestational age alone is a poor predictor of subsequent risk of preterm birth. 2021 Journal Article http://hdl.handle.net/20.500.11937/93227 10.1186/s12884-021-04084-x English http://purl.org/au-research/grants/nhmrc/1099655 http://purl.org/au-research/grants/nhmrc/1173991 http://purl.org/au-research/grants/nhmrc/1195716 http://creativecommons.org/licenses/by/4.0/ BMC fulltext
spellingShingle Science & Technology
Life Sciences & Biomedicine
Obstetrics & Gynecology
Premature birth
Gestational age
Recurrence
Predictive value of tests
Sensitivity and specificity
RECURRENCE RISK
HEALTH
Gestational age
Predictive value of tests
Premature birth
Recurrence
Sensitivity and specificity
Adult
Australia
Birth Order
Female
Gestational Age
Gravidity
Humans
Infant, Newborn
New South Wales
Parity
Pregnancy
Premature Birth
Retrospective Studies
Risk Factors
Young Adult
Humans
Premature Birth
Risk Factors
Retrospective Studies
Birth Order
Gravidity
Parity
Gestational Age
Pregnancy
Adult
Infant, Newborn
Australia
New South Wales
Female
Young Adult
Pereira, Gavin
Regan, Annette
Wong, Kingsley
Tessema, Gizachew
Gestational age as a predictor for subsequent preterm birth in New South Wales, Australia
title Gestational age as a predictor for subsequent preterm birth in New South Wales, Australia
title_full Gestational age as a predictor for subsequent preterm birth in New South Wales, Australia
title_fullStr Gestational age as a predictor for subsequent preterm birth in New South Wales, Australia
title_full_unstemmed Gestational age as a predictor for subsequent preterm birth in New South Wales, Australia
title_short Gestational age as a predictor for subsequent preterm birth in New South Wales, Australia
title_sort gestational age as a predictor for subsequent preterm birth in new south wales, australia
topic Science & Technology
Life Sciences & Biomedicine
Obstetrics & Gynecology
Premature birth
Gestational age
Recurrence
Predictive value of tests
Sensitivity and specificity
RECURRENCE RISK
HEALTH
Gestational age
Predictive value of tests
Premature birth
Recurrence
Sensitivity and specificity
Adult
Australia
Birth Order
Female
Gestational Age
Gravidity
Humans
Infant, Newborn
New South Wales
Parity
Pregnancy
Premature Birth
Retrospective Studies
Risk Factors
Young Adult
Humans
Premature Birth
Risk Factors
Retrospective Studies
Birth Order
Gravidity
Parity
Gestational Age
Pregnancy
Adult
Infant, Newborn
Australia
New South Wales
Female
Young Adult
url http://purl.org/au-research/grants/nhmrc/1099655
http://purl.org/au-research/grants/nhmrc/1099655
http://purl.org/au-research/grants/nhmrc/1099655
http://hdl.handle.net/20.500.11937/93227