Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge among Patients Resuscitated after Out-of-Hospital Cardiac Arrest: The EXACT Randomized Clinical Trial

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Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge among Patients Resuscitated after Out-of-Hospital Cardiac Arrest: The EXACT Randomized Clinical Trial

Importance: The administration of a high fraction of oxygen following return of spontaneous circulation in out-of-hospital cardiac arrest may increase reperfusion brain injury. Objective: To determine whether targeting a lower oxygen saturation in the early phase of postresuscitation care for out-of...

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Bibliographic Details
Main Authors:	Bernard, S.A., Bray, Janet, Smith, K., Stephenson, M., Finn, Judith, Grantham, H., Hein, C., Masters, S., Stub, D., Perkins, G.D., Dodge, N., Martin, C., Hopkins, S., Cameron, P.
Format:	Journal Article
Language:	English
Published:	AMER MEDICAL ASSOC 2022
Subjects:	Science & Technology Life Sciences & Biomedicine Medicine, General & Internal General & Internal Medicine INTERNATIONAL LIAISON COMMITTEE AMERICAN-HEART-ASSOCIATION HEALTH-CARE PROFESSIONALS EUROPEAN RESUSCITATION STROKE FOUNDATION OUTCOME REPORTS TASK-FORCE HYPEROXIA METAANALYSIS COUNCIL Adult Humans Female Aged Male Out-of-Hospital Cardiac Arrest Cardiopulmonary Resuscitation Patient Discharge Oxygen Pandemics COVID-19 Oxygen Saturation Oxygen Inhalation Therapy Hospitals Victoria EXACT Investigators
Online Access:	http://purl.org/au-research/grants/nhmrc/1107509 http://hdl.handle.net/20.500.11937/93113

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