Factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: A Cross-sectional Study
BACKGROUND: Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
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OXFORD UNIV PRESS
2020
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| Subjects: | |
| Online Access: | http://purl.org/au-research/grants/nhmrc/1136372 http://hdl.handle.net/20.500.11937/93103 |
| _version_ | 1848765698591948800 |
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| author | Chowdhury, Enayet Nelson, M.R. Ernst, M.E. Margolis, K.L. Beilin, L.J. Johnston, C.I. Woods, R.L. Murray, A.M. Wolfe, R. Storey, E. Shah, R.C. Lockery, J.E. Tonkin, A.M. Newman, A.B. Williamson, J.D. Abhayaratna, W.P. Stocks, N.P. Fitzgerald, S.M. Orchard, S.G. Trevaks, R.E. Donnan, G.A. Grimm, R. McNeil, J.J. Reid, Christopher |
| author_facet | Chowdhury, Enayet Nelson, M.R. Ernst, M.E. Margolis, K.L. Beilin, L.J. Johnston, C.I. Woods, R.L. Murray, A.M. Wolfe, R. Storey, E. Shah, R.C. Lockery, J.E. Tonkin, A.M. Newman, A.B. Williamson, J.D. Abhayaratna, W.P. Stocks, N.P. Fitzgerald, S.M. Orchard, S.G. Trevaks, R.E. Donnan, G.A. Grimm, R. McNeil, J.J. Reid, Christopher |
| author_sort | Chowdhury, Enayet |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | BACKGROUND: Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants free from overt cardiovascular disease (CVD), and identified factors related to both “untreated” and “treated but uncontrolled” high BP.
METHODS: We analyzed baseline data from 19,114 individuals aged ≥65 years enrolled from Australia and United States (US) in the ASPirin in Reducing Events in the Elderly study. Hypertension was defined as an average systolic/diastolic BP ≥140/90 mm Hg and/or the use of any BP lowering medication. “Controlled hypertension” was defined if participants were receiving antihypertensive medication and BP <140 and 90 mm Hg. Descriptive analyses were used to summarize hypertension control rates; logistic regression was used to investigate relationships with treatment and BP control.
RESULTS: Overall, 74% (14,213/19,114) of participants were hypertensive; and of these 29% (4,151/14,213) were untreated. Among those treated participants, 53% (5,330/10,062) had BP ≥140/90 mm Hg. Participants who were untreated were more likely to be men, have higher educational status, and be in good physical health, and less likely to have significant comorbidities. The factors related to “treated but uncontrolled” BP included older age, male, Black race (vs. White), using antihypertensive monotherapy (vs. multiple) and residing in Australia (vs. US).
CONCLUSIONS: High levels of “untreated” and “treated but uncontrolled” BP occur in healthy elderly people without CVD, suggesting there are opportunities for better BP control in the primary prevention of CVD in this population. |
| first_indexed | 2025-11-14T11:39:23Z |
| format | Journal Article |
| id | curtin-20.500.11937-93103 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T11:39:23Z |
| publishDate | 2020 |
| publisher | OXFORD UNIV PRESS |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-931032023-09-06T01:25:00Z Factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: A Cross-sectional Study Chowdhury, Enayet Nelson, M.R. Ernst, M.E. Margolis, K.L. Beilin, L.J. Johnston, C.I. Woods, R.L. Murray, A.M. Wolfe, R. Storey, E. Shah, R.C. Lockery, J.E. Tonkin, A.M. Newman, A.B. Williamson, J.D. Abhayaratna, W.P. Stocks, N.P. Fitzgerald, S.M. Orchard, S.G. Trevaks, R.E. Donnan, G.A. Grimm, R. McNeil, J.J. Reid, Christopher Science & Technology Life Sciences & Biomedicine Peripheral Vascular Disease Cardiovascular System & Cardiology antihypertensive blood pressure BP control elderly hypertension NUTRITION EXAMINATION SURVEY BLOOD-PRESSURE CONTROL REDUCING EVENTS NATIONAL-HEALTH PREVALENCE ASPIRIN ASPREE ADULTS TRENDS Science & Technology Life Sciences & Biomedicine Cardiac & Cardiovascular Systems Cardiovascular System & Cardiology BP control antihypertensive blood pressure elderly hypertension Age Factors Aged Antihypertensive Agents Australia Blood Pressure Cross-Sectional Studies Female Humans Hypertension Male Prevalence Randomized Controlled Trials as Topic Risk Assessment Risk Factors Treatment Outcome United States ASPREE Investigator Group Humans Hypertension Antihypertensive Agents Treatment Outcome Prevalence Risk Assessment Risk Factors Cross-Sectional Studies Age Factors Blood Pressure Aged United States Australia Female Male Randomized Controlled Trials as Topic BACKGROUND: Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants free from overt cardiovascular disease (CVD), and identified factors related to both “untreated” and “treated but uncontrolled” high BP. METHODS: We analyzed baseline data from 19,114 individuals aged ≥65 years enrolled from Australia and United States (US) in the ASPirin in Reducing Events in the Elderly study. Hypertension was defined as an average systolic/diastolic BP ≥140/90 mm Hg and/or the use of any BP lowering medication. “Controlled hypertension” was defined if participants were receiving antihypertensive medication and BP <140 and 90 mm Hg. Descriptive analyses were used to summarize hypertension control rates; logistic regression was used to investigate relationships with treatment and BP control. RESULTS: Overall, 74% (14,213/19,114) of participants were hypertensive; and of these 29% (4,151/14,213) were untreated. Among those treated participants, 53% (5,330/10,062) had BP ≥140/90 mm Hg. Participants who were untreated were more likely to be men, have higher educational status, and be in good physical health, and less likely to have significant comorbidities. The factors related to “treated but uncontrolled” BP included older age, male, Black race (vs. White), using antihypertensive monotherapy (vs. multiple) and residing in Australia (vs. US). CONCLUSIONS: High levels of “untreated” and “treated but uncontrolled” BP occur in healthy elderly people without CVD, suggesting there are opportunities for better BP control in the primary prevention of CVD in this population. 2020 Journal Article http://hdl.handle.net/20.500.11937/93103 10.1093/ajh/hpz192 English http://purl.org/au-research/grants/nhmrc/1136372 OXFORD UNIV PRESS unknown |
| spellingShingle | Science & Technology Life Sciences & Biomedicine Peripheral Vascular Disease Cardiovascular System & Cardiology antihypertensive blood pressure BP control elderly hypertension NUTRITION EXAMINATION SURVEY BLOOD-PRESSURE CONTROL REDUCING EVENTS NATIONAL-HEALTH PREVALENCE ASPIRIN ASPREE ADULTS TRENDS Science & Technology Life Sciences & Biomedicine Cardiac & Cardiovascular Systems Cardiovascular System & Cardiology BP control antihypertensive blood pressure elderly hypertension Age Factors Aged Antihypertensive Agents Australia Blood Pressure Cross-Sectional Studies Female Humans Hypertension Male Prevalence Randomized Controlled Trials as Topic Risk Assessment Risk Factors Treatment Outcome United States ASPREE Investigator Group Humans Hypertension Antihypertensive Agents Treatment Outcome Prevalence Risk Assessment Risk Factors Cross-Sectional Studies Age Factors Blood Pressure Aged United States Australia Female Male Randomized Controlled Trials as Topic Chowdhury, Enayet Nelson, M.R. Ernst, M.E. Margolis, K.L. Beilin, L.J. Johnston, C.I. Woods, R.L. Murray, A.M. Wolfe, R. Storey, E. Shah, R.C. Lockery, J.E. Tonkin, A.M. Newman, A.B. Williamson, J.D. Abhayaratna, W.P. Stocks, N.P. Fitzgerald, S.M. Orchard, S.G. Trevaks, R.E. Donnan, G.A. Grimm, R. McNeil, J.J. Reid, Christopher Factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: A Cross-sectional Study |
| title | Factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: A Cross-sectional Study |
| title_full | Factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: A Cross-sectional Study |
| title_fullStr | Factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: A Cross-sectional Study |
| title_full_unstemmed | Factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: A Cross-sectional Study |
| title_short | Factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: A Cross-sectional Study |
| title_sort | factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: a cross-sectional study |
| topic | Science & Technology Life Sciences & Biomedicine Peripheral Vascular Disease Cardiovascular System & Cardiology antihypertensive blood pressure BP control elderly hypertension NUTRITION EXAMINATION SURVEY BLOOD-PRESSURE CONTROL REDUCING EVENTS NATIONAL-HEALTH PREVALENCE ASPIRIN ASPREE ADULTS TRENDS Science & Technology Life Sciences & Biomedicine Cardiac & Cardiovascular Systems Cardiovascular System & Cardiology BP control antihypertensive blood pressure elderly hypertension Age Factors Aged Antihypertensive Agents Australia Blood Pressure Cross-Sectional Studies Female Humans Hypertension Male Prevalence Randomized Controlled Trials as Topic Risk Assessment Risk Factors Treatment Outcome United States ASPREE Investigator Group Humans Hypertension Antihypertensive Agents Treatment Outcome Prevalence Risk Assessment Risk Factors Cross-Sectional Studies Age Factors Blood Pressure Aged United States Australia Female Male Randomized Controlled Trials as Topic |
| url | http://purl.org/au-research/grants/nhmrc/1136372 http://hdl.handle.net/20.500.11937/93103 |