Obesity, dieting, and multiple sclerosis

Background: Obesity is common in the United States and is associated with a higher risk of relapse and comorbidities, and increased disease progression, in people with MS. Methods: We examined the prevalence of overweight and obesity in the MS Sunshine Study, a matched case-control study of multiple...

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Bibliographic Details
Main Authors: Russell, Rebecca, Langer-Gould, A., Gonzales, E.G., Smith, J.B., Brennan, Vanessa, Pereira, Gavin, Lucas, R.M., Begley, Andrea, Black, Lucinda
Format: Journal Article
Language:English
Published: ELSEVIER SCI LTD 2020
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Online Access:http://hdl.handle.net/20.500.11937/92916
Description
Summary:Background: Obesity is common in the United States and is associated with a higher risk of relapse and comorbidities, and increased disease progression, in people with MS. Methods: We examined the prevalence of overweight and obesity in the MS Sunshine Study, a matched case-control study of multiple sclerosis in Southern California (470 cases, 519 controls). We reported the proportion of participants who adopted a specific diet for nutrition or weight loss purposes, and identified independent predictors of dieting. Results: In the total population, 32% and 37% were overweight and obese, respectively. Case participants were no more likely to adopt a specific diet for nutrition or weight loss purposes than control participants (10% and 11%, respectively). Being obese, younger, female or non-Hispanic were independently associated with dieting. Conclusion: Despite the evidence that obesity can worsen MS prognosis, and the high prevalence of overweight/obesity, case participants were no more likely to adopt a specific diet than control participants. Improved nutrition education may help people with MS make healthy dietary changes for nutrition or weight loss purposes.