Understanding Proteolytic Processing of Melanoma Cell Adhesion Molecule (MCAM) in Cutaneous Melanoma
Melanoma is a type of skin cancer and is one of the most common cancers in Australia. Due to the aggressive nature of melanoma, an improved understanding of its progression is required. In this thesis, the processing of “Melanoma Cell Adhesion Molecule” (MCAM), a protein that contributes to melanoma...
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| Format: | Thesis |
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Curtin University
2023
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| Online Access: | http://hdl.handle.net/20.500.11937/92799 |
| _version_ | 1848765667497476096 |
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| author | George, Tenielle |
| author_facet | George, Tenielle |
| author_sort | George, Tenielle |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Melanoma is a type of skin cancer and is one of the most common cancers in Australia. Due to the aggressive nature of melanoma, an improved understanding of its progression is required. In this thesis, the processing of “Melanoma Cell Adhesion Molecule” (MCAM), a protein that contributes to melanoma metastasis, was explored in detail. In particular, we found that MCAM undergoes at least two cleavage events, generating protein fragments that likely contribute to melanoma spread. |
| first_indexed | 2025-11-14T11:38:54Z |
| format | Thesis |
| id | curtin-20.500.11937-92799 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:38:54Z |
| publishDate | 2023 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-927992023-07-21T03:22:04Z Understanding Proteolytic Processing of Melanoma Cell Adhesion Molecule (MCAM) in Cutaneous Melanoma George, Tenielle Melanoma is a type of skin cancer and is one of the most common cancers in Australia. Due to the aggressive nature of melanoma, an improved understanding of its progression is required. In this thesis, the processing of “Melanoma Cell Adhesion Molecule” (MCAM), a protein that contributes to melanoma metastasis, was explored in detail. In particular, we found that MCAM undergoes at least two cleavage events, generating protein fragments that likely contribute to melanoma spread. 2023 Thesis http://hdl.handle.net/20.500.11937/92799 Curtin University fulltext |
| spellingShingle | George, Tenielle Understanding Proteolytic Processing of Melanoma Cell Adhesion Molecule (MCAM) in Cutaneous Melanoma |
| title | Understanding Proteolytic Processing of Melanoma Cell
Adhesion Molecule (MCAM) in Cutaneous Melanoma |
| title_full | Understanding Proteolytic Processing of Melanoma Cell
Adhesion Molecule (MCAM) in Cutaneous Melanoma |
| title_fullStr | Understanding Proteolytic Processing of Melanoma Cell
Adhesion Molecule (MCAM) in Cutaneous Melanoma |
| title_full_unstemmed | Understanding Proteolytic Processing of Melanoma Cell
Adhesion Molecule (MCAM) in Cutaneous Melanoma |
| title_short | Understanding Proteolytic Processing of Melanoma Cell
Adhesion Molecule (MCAM) in Cutaneous Melanoma |
| title_sort | understanding proteolytic processing of melanoma cell
adhesion molecule (mcam) in cutaneous melanoma |
| url | http://hdl.handle.net/20.500.11937/92799 |