| Summary: | Despite advancements in the current standard of care, cardiovascular diseases continue to
hold the top spot as the leading cause of mortality worldwide. The development of atherosclerosis
is the most common culprit behind ailments such as myocardial infarction, stroke, and peripheral
vascular disease. Consequently, it imposes a significant burden on life expectancy, quality of life,
morbidity, and societal costs. Both increased cholesterol levels and the activation of the inflammatory
cascade are known as cardiovascular risk facts. Their relative weight is in the spotlight of curent
biomedical research. Newly published data shed light on the role of inflammation in determining
cardiovascular risk irrespective of cholesterol levels and cholesterol-lowering therapies
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