Should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose?
Heroin overdose is a major cause of death among heroin users, and often occurs in the company of other users. However, sudden death after injection is rare, giving ample opportunity for intervention.Naloxone hydrochloride, an injectable opioid antagonist which reverses the respiratory depression, se...
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| Format: | Journal Article |
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2000
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| Online Access: | http://www.mja.com.au/public/issues/173_05_040900/lenton/lenton.html http://hdl.handle.net/20.500.11937/9038 |
| _version_ | 1848745834183655424 |
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| author | Lenton, Simon Hargreaves, K. |
| author_facet | Lenton, Simon Hargreaves, K. |
| author_sort | Lenton, Simon |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Heroin overdose is a major cause of death among heroin users, and often occurs in the company of other users. However, sudden death after injection is rare, giving ample opportunity for intervention.Naloxone hydrochloride, an injectable opioid antagonist which reverses the respiratory depression, sedation and hypotension associated with opioids, has long been used to treat opioid overdose.Experts have suggested that, as part of a comprehensive overdose prevention strategy, naloxone should be provided to heroin users for peer administration after an overdose.A trial could be conducted to determine whether this intervention improves the management of overdose or results in a net increase in harm (by undermining existing prevention strategies, precipitating naloxone-related complications, or resulting in riskier heroin use). |
| first_indexed | 2025-11-14T06:23:39Z |
| format | Journal Article |
| id | curtin-20.500.11937-9038 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T06:23:39Z |
| publishDate | 2000 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-90382017-01-30T11:10:07Z Should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose? Lenton, Simon Hargreaves, K. drug - heroin - overdose - naloxone - drug - harm reduction - peer - legal aspects - evaluation - mortality - morbidity - death - resuscitation Heroin overdose is a major cause of death among heroin users, and often occurs in the company of other users. However, sudden death after injection is rare, giving ample opportunity for intervention.Naloxone hydrochloride, an injectable opioid antagonist which reverses the respiratory depression, sedation and hypotension associated with opioids, has long been used to treat opioid overdose.Experts have suggested that, as part of a comprehensive overdose prevention strategy, naloxone should be provided to heroin users for peer administration after an overdose.A trial could be conducted to determine whether this intervention improves the management of overdose or results in a net increase in harm (by undermining existing prevention strategies, precipitating naloxone-related complications, or resulting in riskier heroin use). 2000 Journal Article http://hdl.handle.net/20.500.11937/9038 http://www.mja.com.au/public/issues/173_05_040900/lenton/lenton.html restricted |
| spellingShingle | drug - heroin - overdose - naloxone - drug - harm reduction - peer - legal aspects - evaluation - mortality - morbidity - death - resuscitation Lenton, Simon Hargreaves, K. Should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose? |
| title | Should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose? |
| title_full | Should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose? |
| title_fullStr | Should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose? |
| title_full_unstemmed | Should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose? |
| title_short | Should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose? |
| title_sort | should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose? |
| topic | drug - heroin - overdose - naloxone - drug - harm reduction - peer - legal aspects - evaluation - mortality - morbidity - death - resuscitation |
| url | http://www.mja.com.au/public/issues/173_05_040900/lenton/lenton.html http://hdl.handle.net/20.500.11937/9038 |