Coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease

Whilst a correlation has been established between wide left main coronary artery bifurcation (LAD-LCx) angle (>80º) and the development of coronary artery disease (CAD), this retrospective, causal-comparative pilot study aimed to explore whether a relationship exists between right coronary artery...

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Main Authors: Geerlings-Batt, Jade, Sun, Zhonghua
Format: Journal Article
Published: AME Publishing Company 2023
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/90321
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author Geerlings-Batt, Jade
Sun, Zhonghua
author_facet Geerlings-Batt, Jade
Sun, Zhonghua
author_sort Geerlings-Batt, Jade
building Curtin Institutional Repository
collection Online Access
description Whilst a correlation has been established between wide left main coronary artery bifurcation (LAD-LCx) angle (>80º) and the development of coronary artery disease (CAD), this retrospective, causal-comparative pilot study aimed to explore whether a relationship exists between right coronary artery (RCA)-aorta angle and CAD. Thirty normal cases were identified via radiology reports and selected as the control group with coronary computed tomography angiography (CCTA) scans performed on a 320-slice computed tomography (CT) scanner. Thirty CAD cases were selected with invasive coronary angiography performed to confirm the degree of stenosis, and CCTA performed on dual source and 320-slice CT scanners. An independent sample T-test was used to compare the differences in coronary angles between the normal and CAD group, and analysis of variance was used to assess for significant differences between coronary angles in normal and CAD subgroups. Coronary angle measurements were conducted by two independent assessors with high intraclass correlation (r=0.971-0.998, p<0.001). RCA-aorta angle measurements were significantly larger in the normal group (87.47°, 95% CI: 79.31°-95.78°) compared to the CAD group (76.82°, 95% CI: 67.82°-85.61° p=0.05). No significant difference was found between RCA-aorta angle and degree of coronary stenosis (p=0.75). This study suggests a relationship between narrow RCA-aorta angle and CAD.
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spelling curtin-20.500.11937-903212023-03-01T01:47:37Z Coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease Geerlings-Batt, Jade Sun, Zhonghua 1102 - Cardiorespiratory Medicine And Haematology 3201 - Cardiovascular medicine and haematology Whilst a correlation has been established between wide left main coronary artery bifurcation (LAD-LCx) angle (>80º) and the development of coronary artery disease (CAD), this retrospective, causal-comparative pilot study aimed to explore whether a relationship exists between right coronary artery (RCA)-aorta angle and CAD. Thirty normal cases were identified via radiology reports and selected as the control group with coronary computed tomography angiography (CCTA) scans performed on a 320-slice computed tomography (CT) scanner. Thirty CAD cases were selected with invasive coronary angiography performed to confirm the degree of stenosis, and CCTA performed on dual source and 320-slice CT scanners. An independent sample T-test was used to compare the differences in coronary angles between the normal and CAD group, and analysis of variance was used to assess for significant differences between coronary angles in normal and CAD subgroups. Coronary angle measurements were conducted by two independent assessors with high intraclass correlation (r=0.971-0.998, p<0.001). RCA-aorta angle measurements were significantly larger in the normal group (87.47°, 95% CI: 79.31°-95.78°) compared to the CAD group (76.82°, 95% CI: 67.82°-85.61° p=0.05). No significant difference was found between RCA-aorta angle and degree of coronary stenosis (p=0.75). This study suggests a relationship between narrow RCA-aorta angle and CAD. 2023 Journal Article http://hdl.handle.net/20.500.11937/90321 10.21037/qims-22-655 http://creativecommons.org/licenses/by-nc-nd/4.0/ AME Publishing Company fulltext
spellingShingle 1102 - Cardiorespiratory Medicine And Haematology
3201 - Cardiovascular medicine and haematology
Geerlings-Batt, Jade
Sun, Zhonghua
Coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease
title Coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease
title_full Coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease
title_fullStr Coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease
title_full_unstemmed Coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease
title_short Coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease
title_sort coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease
topic 1102 - Cardiorespiratory Medicine And Haematology
3201 - Cardiovascular medicine and haematology
url http://hdl.handle.net/20.500.11937/90321