Patient and provider perceptions of a peer-delivered intervention ('Khanya') to improve anti-retroviral adherence and substance use in South Africa: a mixed methods analysis

BACKGROUND: Despite a high prevalence of problematic substance use among people living with HIV in South Africa, there remains limited access to substance use services within the HIV care system. To address this gap, our team previously developed and adapted a six-session, peer-delivered problem-sol...

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Main Authors: Rose, Alexandra L, Belus, Jennifer M, Hines, Abigail C, Barrie, Issmatu, Regenauer, Kristen S, Andersen, Lena S, Joska, John A, Ciya, Nonceba, Ndamase, Sibabalwe, Myers, Bronwyn, Safren, Steven A, Magidson, Jessica F
Format: Journal Article
Language:English
Published: CAMBRIDGE UNIV PRESS 2022
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/90177
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author Rose, Alexandra L
Belus, Jennifer M
Hines, Abigail C
Barrie, Issmatu
Regenauer, Kristen S
Andersen, Lena S
Joska, John A
Ciya, Nonceba
Ndamase, Sibabalwe
Myers, Bronwyn
Safren, Steven A
Magidson, Jessica F
author_facet Rose, Alexandra L
Belus, Jennifer M
Hines, Abigail C
Barrie, Issmatu
Regenauer, Kristen S
Andersen, Lena S
Joska, John A
Ciya, Nonceba
Ndamase, Sibabalwe
Myers, Bronwyn
Safren, Steven A
Magidson, Jessica F
author_sort Rose, Alexandra L
building Curtin Institutional Repository
collection Online Access
description BACKGROUND: Despite a high prevalence of problematic substance use among people living with HIV in South Africa, there remains limited access to substance use services within the HIV care system. To address this gap, our team previously developed and adapted a six-session, peer-delivered problem-solving and behavioral activation-based intervention (Khanya) to improve HIV medication adherence and reduce substance use in Cape Town. This study evaluated patient and provider perspectives on the intervention to inform implementation and future adaptation. METHODS: Following intervention completion, we conducted semi-structured individual interviews with patients (n = 23) and providers (n = 9) to understand perspectives on the feasibility, acceptability, and appropriateness of Khanya and its implementation by a peer. Patients also quantitatively ranked the usefulness of individual intervention components (problem solving for medication adherence 'Life-Steps', behavioral activation, mindfulness training, and relapse prevention) at post-treatment and six months follow-up, which we triangulated with qualitative feedback to examine convergence and divergence across methods. RESULTS: Patients and providers reported high overall acceptability, feasibility, and appropriateness of Khanya, although there were several feasibility challenges. Mindfulness and Life-Steps were identified as particularly acceptable, feasible, and appropriate components by patients across methods, whereas relapse prevention strategies were less salient. Behavioral activation results were less consistent across methods. CONCLUSIONS: Findings underscore the importance of examining patients' perspectives on specific intervention components within intervention packages. While mindfulness training and peer delivery models were positively perceived by consumers, they are rarely used within task-shared behavioral interventions in low- and middle-income countries.
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spelling curtin-20.500.11937-901772023-02-20T04:20:30Z Patient and provider perceptions of a peer-delivered intervention ('Khanya') to improve anti-retroviral adherence and substance use in South Africa: a mixed methods analysis Rose, Alexandra L Belus, Jennifer M Hines, Abigail C Barrie, Issmatu Regenauer, Kristen S Andersen, Lena S Joska, John A Ciya, Nonceba Ndamase, Sibabalwe Myers, Bronwyn Safren, Steven A Magidson, Jessica F Science & Technology Life Sciences & Biomedicine Psychiatry HIV mindfulness peer South Africa substance-related disorders MIDDLE-INCOME COUNTRIES BEHAVIORAL ACTIVATION DEPRESSION CARE PREFERENCES INTEGRATION THERAPY BACKGROUND: Despite a high prevalence of problematic substance use among people living with HIV in South Africa, there remains limited access to substance use services within the HIV care system. To address this gap, our team previously developed and adapted a six-session, peer-delivered problem-solving and behavioral activation-based intervention (Khanya) to improve HIV medication adherence and reduce substance use in Cape Town. This study evaluated patient and provider perspectives on the intervention to inform implementation and future adaptation. METHODS: Following intervention completion, we conducted semi-structured individual interviews with patients (n = 23) and providers (n = 9) to understand perspectives on the feasibility, acceptability, and appropriateness of Khanya and its implementation by a peer. Patients also quantitatively ranked the usefulness of individual intervention components (problem solving for medication adherence 'Life-Steps', behavioral activation, mindfulness training, and relapse prevention) at post-treatment and six months follow-up, which we triangulated with qualitative feedback to examine convergence and divergence across methods. RESULTS: Patients and providers reported high overall acceptability, feasibility, and appropriateness of Khanya, although there were several feasibility challenges. Mindfulness and Life-Steps were identified as particularly acceptable, feasible, and appropriate components by patients across methods, whereas relapse prevention strategies were less salient. Behavioral activation results were less consistent across methods. CONCLUSIONS: Findings underscore the importance of examining patients' perspectives on specific intervention components within intervention packages. While mindfulness training and peer delivery models were positively perceived by consumers, they are rarely used within task-shared behavioral interventions in low- and middle-income countries. 2022 Journal Article http://hdl.handle.net/20.500.11937/90177 10.1017/gmh.2022.47 English http://creativecommons.org/licenses/by/4.0/ CAMBRIDGE UNIV PRESS fulltext
spellingShingle Science & Technology
Life Sciences & Biomedicine
Psychiatry
HIV
mindfulness
peer
South Africa
substance-related disorders
MIDDLE-INCOME COUNTRIES
BEHAVIORAL ACTIVATION
DEPRESSION
CARE
PREFERENCES
INTEGRATION
THERAPY
Rose, Alexandra L
Belus, Jennifer M
Hines, Abigail C
Barrie, Issmatu
Regenauer, Kristen S
Andersen, Lena S
Joska, John A
Ciya, Nonceba
Ndamase, Sibabalwe
Myers, Bronwyn
Safren, Steven A
Magidson, Jessica F
Patient and provider perceptions of a peer-delivered intervention ('Khanya') to improve anti-retroviral adherence and substance use in South Africa: a mixed methods analysis
title Patient and provider perceptions of a peer-delivered intervention ('Khanya') to improve anti-retroviral adherence and substance use in South Africa: a mixed methods analysis
title_full Patient and provider perceptions of a peer-delivered intervention ('Khanya') to improve anti-retroviral adherence and substance use in South Africa: a mixed methods analysis
title_fullStr Patient and provider perceptions of a peer-delivered intervention ('Khanya') to improve anti-retroviral adherence and substance use in South Africa: a mixed methods analysis
title_full_unstemmed Patient and provider perceptions of a peer-delivered intervention ('Khanya') to improve anti-retroviral adherence and substance use in South Africa: a mixed methods analysis
title_short Patient and provider perceptions of a peer-delivered intervention ('Khanya') to improve anti-retroviral adherence and substance use in South Africa: a mixed methods analysis
title_sort patient and provider perceptions of a peer-delivered intervention ('khanya') to improve anti-retroviral adherence and substance use in south africa: a mixed methods analysis
topic Science & Technology
Life Sciences & Biomedicine
Psychiatry
HIV
mindfulness
peer
South Africa
substance-related disorders
MIDDLE-INCOME COUNTRIES
BEHAVIORAL ACTIVATION
DEPRESSION
CARE
PREFERENCES
INTEGRATION
THERAPY
url http://hdl.handle.net/20.500.11937/90177