Introducing the crystalline phase of dicalcium phosphate monohydrate
Calcium orthophosphates (CaPs) are important in geology, biomineralization, animal metabolism and biomedicine, and constitute a structurally and chemically diverse class of minerals. In the case of dicalcium phosphates, ever since brushite (CaHPO4·2H2O, dicalcium phosphate dihydrate, DCPD) and monet...
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| Format: | Journal Article |
| Language: | English |
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NATURE PUBLISHING GROUP
2020
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| Online Access: | http://purl.org/au-research/grants/arc/FL180100087 http://hdl.handle.net/20.500.11937/90103 |
| _version_ | 1848765325793820672 |
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| author | Lu, B.Q. Willhammar, T. Sun, B.B. Hedin, N. Gale, Julian Gebauer, Denis |
| author_facet | Lu, B.Q. Willhammar, T. Sun, B.B. Hedin, N. Gale, Julian Gebauer, Denis |
| author_sort | Lu, B.Q. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Calcium orthophosphates (CaPs) are important in geology, biomineralization, animal metabolism and biomedicine, and constitute a structurally and chemically diverse class of minerals. In the case of dicalcium phosphates, ever since brushite (CaHPO4·2H2O, dicalcium phosphate dihydrate, DCPD) and monetite (CaHPO4, dicalcium phosphate, DCP) were first described in 19th century, the form with intermediary chemical formula CaHPO4·H2O (dicalcium phosphate monohydrate, DCPM) has remained elusive. Here, we report the synthesis and crystal structure determination of DCPM. This form of CaP is found to crystallize from amorphous calcium hydrogen phosphate (ACHP) in water-poor environments. The crystal structure of DCPM is determined to show a layered structure with a monoclinic symmetry. DCPM is metastable in water, but can be stabilized by organics, and has a higher alkalinity than DCP and DCPD. This study serves as an inspiration for the future exploration of DCPM’s potential role in biomineralization, or biomedical applications. |
| first_indexed | 2025-11-14T11:33:28Z |
| format | Journal Article |
| id | curtin-20.500.11937-90103 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T11:33:28Z |
| publishDate | 2020 |
| publisher | NATURE PUBLISHING GROUP |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-901032023-01-24T04:13:51Z Introducing the crystalline phase of dicalcium phosphate monohydrate Lu, B.Q. Willhammar, T. Sun, B.B. Hedin, N. Gale, Julian Gebauer, Denis Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics AMORPHOUS CALCIUM-PHOSPHATE ELECTRON-DIFFRACTION DATA DATA-COLLECTION BRUSHITE BONE ORTHOPHOSPHATES MONETITE APATITE CAHPO4-CENTER-DOT-2H(2)O TRANSFORMATION Calcium orthophosphates (CaPs) are important in geology, biomineralization, animal metabolism and biomedicine, and constitute a structurally and chemically diverse class of minerals. In the case of dicalcium phosphates, ever since brushite (CaHPO4·2H2O, dicalcium phosphate dihydrate, DCPD) and monetite (CaHPO4, dicalcium phosphate, DCP) were first described in 19th century, the form with intermediary chemical formula CaHPO4·H2O (dicalcium phosphate monohydrate, DCPM) has remained elusive. Here, we report the synthesis and crystal structure determination of DCPM. This form of CaP is found to crystallize from amorphous calcium hydrogen phosphate (ACHP) in water-poor environments. The crystal structure of DCPM is determined to show a layered structure with a monoclinic symmetry. DCPM is metastable in water, but can be stabilized by organics, and has a higher alkalinity than DCP and DCPD. This study serves as an inspiration for the future exploration of DCPM’s potential role in biomineralization, or biomedical applications. 2020 Journal Article http://hdl.handle.net/20.500.11937/90103 10.1038/s41467-020-15333-6 English http://purl.org/au-research/grants/arc/FL180100087 http://creativecommons.org/licenses/by/4.0/ NATURE PUBLISHING GROUP fulltext |
| spellingShingle | Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics AMORPHOUS CALCIUM-PHOSPHATE ELECTRON-DIFFRACTION DATA DATA-COLLECTION BRUSHITE BONE ORTHOPHOSPHATES MONETITE APATITE CAHPO4-CENTER-DOT-2H(2)O TRANSFORMATION Lu, B.Q. Willhammar, T. Sun, B.B. Hedin, N. Gale, Julian Gebauer, Denis Introducing the crystalline phase of dicalcium phosphate monohydrate |
| title | Introducing the crystalline phase of dicalcium phosphate monohydrate |
| title_full | Introducing the crystalline phase of dicalcium phosphate monohydrate |
| title_fullStr | Introducing the crystalline phase of dicalcium phosphate monohydrate |
| title_full_unstemmed | Introducing the crystalline phase of dicalcium phosphate monohydrate |
| title_short | Introducing the crystalline phase of dicalcium phosphate monohydrate |
| title_sort | introducing the crystalline phase of dicalcium phosphate monohydrate |
| topic | Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics AMORPHOUS CALCIUM-PHOSPHATE ELECTRON-DIFFRACTION DATA DATA-COLLECTION BRUSHITE BONE ORTHOPHOSPHATES MONETITE APATITE CAHPO4-CENTER-DOT-2H(2)O TRANSFORMATION |
| url | http://purl.org/au-research/grants/arc/FL180100087 http://hdl.handle.net/20.500.11937/90103 |