Ubiquinone electrochemistry in analysis and sensing

Ubiquinone (UQ) is a lipophilic compound present in most living organisms,where UQ’s interesting but complex electrochemistry serves an important rolein the transfer of electrons and protons within and across the mitochondrialmembrane. We briefly review the electrochemical characteristics of UQ and...

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Main Authors: O Conghaile, Peter, Arrigan, Damien
Format: Journal Article
Published: 2022
Subjects:
Online Access:European Commission’s Marie Skłodowska Curie Actions Global Fellowship Program. Project name: VITAL-ISE, Development and application of ion-sensors for multi-analyte detection, European Commission Grant Agreement ID: 846027
http://hdl.handle.net/20.500.11937/89588
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author O Conghaile, Peter
Arrigan, Damien
author_facet O Conghaile, Peter
Arrigan, Damien
author_sort O Conghaile, Peter
building Curtin Institutional Repository
collection Online Access
description Ubiquinone (UQ) is a lipophilic compound present in most living organisms,where UQ’s interesting but complex electrochemistry serves an important rolein the transfer of electrons and protons within and across the mitochondrialmembrane. We briefly review the electrochemical characteristics of UQ and itsreduced state, ubiquinol, in solution and immobilized on electrodes, togetherwith its application in electrochemical sensing and detection systems, for exam-ple, measuring redox status with reference to reactive oxidative species. Theimportance of the local environment, solvent, electrolyte, organic membrane,and pH, on the electrochemical behavior of UQ, is also discussed. We discusstechniques used for the direct detection of UQ such as liquid chromatography-electrochemistry. Mediated electrochemistry of UQ allows for quantitative mea-surements of ions, small molecules, and other analytes such as glucose via chem-ical sensors and biosensors.
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spelling curtin-20.500.11937-895882022-12-02T09:09:09Z Ubiquinone electrochemistry in analysis and sensing O Conghaile, Peter Arrigan, Damien 0301 - Analytical Chemistry 0306 - Physical Chemistry (incl. Structural) Ubiquinone (UQ) is a lipophilic compound present in most living organisms,where UQ’s interesting but complex electrochemistry serves an important rolein the transfer of electrons and protons within and across the mitochondrialmembrane. We briefly review the electrochemical characteristics of UQ and itsreduced state, ubiquinol, in solution and immobilized on electrodes, togetherwith its application in electrochemical sensing and detection systems, for exam-ple, measuring redox status with reference to reactive oxidative species. Theimportance of the local environment, solvent, electrolyte, organic membrane,and pH, on the electrochemical behavior of UQ, is also discussed. We discusstechniques used for the direct detection of UQ such as liquid chromatography-electrochemistry. Mediated electrochemistry of UQ allows for quantitative mea-surements of ions, small molecules, and other analytes such as glucose via chem-ical sensors and biosensors. 2022 Journal Article http://hdl.handle.net/20.500.11937/89588 10.1002/elsa.202100214 European Commission’s Marie Skłodowska Curie Actions Global Fellowship Program. Project name: VITAL-ISE, Development and application of ion-sensors for multi-analyte detection, European Commission Grant Agreement ID: 846027 http://creativecommons.org/licenses/by-nc-nd/4.0/ fulltext
spellingShingle 0301 - Analytical Chemistry
0306 - Physical Chemistry (incl. Structural)
O Conghaile, Peter
Arrigan, Damien
Ubiquinone electrochemistry in analysis and sensing
title Ubiquinone electrochemistry in analysis and sensing
title_full Ubiquinone electrochemistry in analysis and sensing
title_fullStr Ubiquinone electrochemistry in analysis and sensing
title_full_unstemmed Ubiquinone electrochemistry in analysis and sensing
title_short Ubiquinone electrochemistry in analysis and sensing
title_sort ubiquinone electrochemistry in analysis and sensing
topic 0301 - Analytical Chemistry
0306 - Physical Chemistry (incl. Structural)
url European Commission’s Marie Skłodowska Curie Actions Global Fellowship Program. Project name: VITAL-ISE, Development and application of ion-sensors for multi-analyte detection, European Commission Grant Agreement ID: 846027
http://hdl.handle.net/20.500.11937/89588