In-vitro Evidence for Novel, Non-Classical, Alternative
P450scc-Initiated Vitamin D Metabolic Pathways in Human
Placenta via HPLC-UV/DAD and LC-ESI-MS/MS Analysis

QR Code

In-vitro Evidence for Novel, Non-Classical, Alternative P450scc-Initiated Vitamin D Metabolic Pathways in Human Placenta via HPLC-UV/DAD and LC-ESI-MS/MS Analysis

Current findings identify and substantiate existence of previously unrecognised, likely, in-vivo alternative, non-classical P450scc-initiated vitamin D3/D2 metabolic pathways within in-vitro human placenta models. These pathways are further modified by CYP27A1 or CYP27B1 activity in human placenta a...

Full description

Bibliographic Details
Main Author:	Shehabi, Haleem Ziad
Format:	Thesis
Published:	Curtin University 2020
Online Access:	http://hdl.handle.net/20.500.11937/89121

Similar Items

Identification of chemical constituents from fruit of Antidesma bunius by GC-MS and HPLC-DAD-ESI-MS
by: Yelliantty, et al.
Published: (2021)

Characterization of polyphenols in Australian sweet lupin (Lupinus angustifolius) seed coat by HPLC-DAD-ESI-MS/MS
by: Zhong, L., et al.
Published: (2018)

Determination of specific iron chelator by using LC-ICP-MS and LC-ESI-MS
by: Mohamed, Khairul Nizam, et al.
Published: (2015)

Detection of antioxidant constituents from Persicaria hydropiper using LC-UV-DAD-ESIM/MS.
by: Noor Hashim, Noor Haslinda
Published: (2011)

LC-DAD-ESI-MS analysis of nitric oxide inhibitory fractions of tenggek burung (Melicope ptelefolia Champ. ex Benth)
by: Abas, Faridah, et al.
Published: (2010)

Rapid detection and identification of Dioscorea compounds in Dioscorea hispada tuber plants by LC-ESI-MS
by: Kamaruddin, Z. H., et al.
Published: (2020)

In vivo evidence for a novel pathway of vitamin D3 metabolism initiated by P450scc and modified by CYP27B1
by: Slominski, A., et al.
Published: (2012)

Optimization method for simultaneous extraction and detection of imazapic and imazapyr herbicides in soil and water using HPLC-UV with verification of LC-MS
by: Bajrai F.S.M.,, et al.
Published: (2017)

Production of 22-hydroxy-metabolites of vitamin D3 by cytochrome P450scc (CYP11A1) and analysis of their biological activities on skin cells
by: Tuckey, R., et al.
Published: (2011)

Production of 22-hydroxy-metabolites of vitamin D3 by cytochrome P450scc (CYP11A1) and analysis of their biological activities on skin cells
by: Tuckey, R., et al.
Published: (2011)

Effect of a different mobile phase on LC–ESI–MS/MS performance for the identification and quantitation of polar and nonpolar heterocyclic amines in cooked chicken
by: Selamat, Jinap, et al.
Published: (2020)

Composition of docosahexaenoic acid, eicosapentaenoic acid and palmitoleic acid in Eucheuma denticulatum, Sargassum polycystum and Caulerpa lentillifera ethanolic extracts by LC-ESI-MS/MS
by: Balasubramaniam, Vimala, et al.
Published: (2018)

LC-ESI-Q-TOF-MS identification of porcine-specific peptide biomarker in cooked pork for halal authentication
by: Zainal Abidin, Siti Aimi Sarah, et al.
Published: (2014)

Phytochemical, bioactivity and LC-DAD-MS/MS analyses of nam-nam (Cynometra cauliflora L.) and tampang besi (Callicarpa maingayi K. & G.) leaf extracts
by: Ado, Muhammad Abubakar
Published: (2016)

Identification and quantification of native beta-casomorphins in Australian milk by LC-MS/MS and LC-HRMS
by: Nguyen, D., et al.
Published: (2015)

Identification of phytochemicals of Phoenix dactylifera L. Cv Ajwa with UHPLC-ESI-QTOF-MS/MS
by: Najm, Omaima Adil, et al.
Published: (2021)

Acrylamide by QuEChERS extraction with LC-MS-MS detection
by: Kinsella, Brian
Published: (2012)

In vitro anti-diabetic activities and UHPLC-ESI-MS/MS profile of Muntingia calabura leaves extract
by: Zolkeflee, Nur Khaleeda Zulaikha, et al.
Published: (2022)

Development of LC/MS-MS method for analysis of polyphenols in Malaysian traditional vegetables
by: Haron, Normah, et al.
Published: (2015)

Ion pairing LC-MS/MS method for analysis of intracellular phosphorylated metabolites
by: Utami, Wahyu
Published: (2015)

LC-MS/MS simulatneous determination of itopride hydrochloride and domperidone in human plasma
by: Bose, Anirbandeep, et al.
Published: (2009)

Detection of bioactive compounds in persimmon (Diospyros kaki) using UPLC-ESI-Orbitrap-MS/MS and fluorescence analyses
by: Maulidiani, M., et al.
Published: (2019)

Antioxidant activity, α-Glucosidase inhibition and UHPLC–ESI–MS/MS profile of Shmar (Arbutus pavarii Pamp)
by: Buzgaia, Nawal, et al.
Published: (2021)

In vitro antidiabetic property and phytochemical profiling of Mangifera odorata pulp using UHPLC-ESI-Orbitrap-MS/MS
by: Lasano, Nur Fatimah, et al.
Published: (2021)

Development, Optimization and Validation of LC-MS/MS Method for Multi-Mycotoxin Detection in Cereals
by: Soleimany, Farhang
Published: (2011)

Analysis of Pseudomonas sp. polycyclic aromatic hydrocarbons degradation proteins by LC-MS/MS
by: Adenan, Suzana, et al.
Published: (2022)

NMR-based metabolomics and UHPLC-ESI-MS/MS profiling of Syzygium jambos in relation to their antioxidant and anti-hyperglycemic activities
by: Wong, Pei Lou, et al.
Published: (2024)

NMR-based metabolomics and UHPLC-ESI-MS/MS profiling of Syzygium jambos in relation to their antioxidant and anti-hyperglucemic activities
by: Abas, Faridah, et al.
Published: (2024)

LC-MS/MS-based metabolites of Eurycoma longifolia (Tongkat Ali) in Malaysia (Perak and Pahang).
by: Mohd Amin, Nor Amaiza, et al.
Published: (2011)

Phytochemical analysis of ethanolic Psidium guajava leaves extract using GC-MS and LC-MS
by: Nursanty, Risa, et al.
Published: (2023)

Development of HPLC-MS/MS method for simultaneus quantification of veterinary antibiotics and hormones in soil and biosolids
by: Ho, Yu Bin
Published: (2012)

Development and validation of a LC- MS/MS Method for simultaneous quantitation of telmisartan and pioglitazone in rat plasma
by: Das, Arindam, et al.
Published: (2016)

LC-MS/MS Analysis Of Plasma Homocysteine And Investigation On The Association Of Homocysteine Levels With Diabetic Peripheral Neuropathy
by: Lim, Luen Hui
Published: (2015)

LC-MS/MS and GC-MS analysis for the identification of bioactive metabolites responsible for the antioxidant and antibacterial activities of Lygodium microphyllum (Cav.) R. Br
by: Teoh, Wuen Yew, et al.
Published: (2023)

Lc-Ms/Ms Profiling and Characterization of Active Components from Medicinal Gingers (Curcuma Xanthorrhiza and Zingiber Zerumbet)
by: Ruslay, Sharin
Published: (2006)

An improved SPE-LC-MS/MS method for multiclass endocrine disrupting compound determination in tropical estuarine sediments
by: Tuan Omar, Tuan Fauzan, et al.
Published: (2017)

Analysis of trehalulose in kelulut honey samples via HPLC-MS
by: J., Arif Zaidi, et al.
Published: (2023)

α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar
by: Lawal, Umar, et al.
Published: (2016)

α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar
by: Lawal, Umar, et al.
Published: (2017)

Identification of chemical compounds from agarwood hydrosol (Aquilaria malaccensis) fruits via LC-QTOF-MS/MS analysis
by: Mohamad Azharishah, Satar, et al.

Cannot write session to /tmp/vufind_sessions/sess_dhfu5g0b5l5dsi8lb1sptjqmlr