Ageing and Mesothelioma Drive Lipid Accumulation and Dysfunction in Dendritic Cells and Macrophages
The goal of this research was to examine the combined effect of ageing and mesothelioma (an untreatable and aggressive cancer) on key innate immune cells, namely macrophages and dendritic cells. Functional and metabolic changes to macrophages and dendritic cells in young and elderly hosts with or wi...
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| Format: | Thesis |
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Curtin University
2022
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| Online Access: | http://hdl.handle.net/20.500.11937/88901 |
| _version_ | 1848765107524337664 |
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| author | Sheeraz, Mohd |
| author_facet | Sheeraz, Mohd |
| author_sort | Sheeraz, Mohd |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The goal of this research was to examine the combined effect of ageing and mesothelioma (an untreatable and aggressive cancer) on key innate immune cells, namely macrophages and dendritic cells. Functional and metabolic changes to macrophages and dendritic cells in young and elderly hosts with or without mesothelioma were examined. The data show that mesothelioma compromised immune function, this was worsened by ageing. |
| first_indexed | 2025-11-14T11:30:00Z |
| format | Thesis |
| id | curtin-20.500.11937-88901 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:30:00Z |
| publishDate | 2022 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-889012024-07-31T05:40:09Z Ageing and Mesothelioma Drive Lipid Accumulation and Dysfunction in Dendritic Cells and Macrophages Sheeraz, Mohd The goal of this research was to examine the combined effect of ageing and mesothelioma (an untreatable and aggressive cancer) on key innate immune cells, namely macrophages and dendritic cells. Functional and metabolic changes to macrophages and dendritic cells in young and elderly hosts with or without mesothelioma were examined. The data show that mesothelioma compromised immune function, this was worsened by ageing. 2022 Thesis http://hdl.handle.net/20.500.11937/88901 Curtin University fulltext |
| spellingShingle | Sheeraz, Mohd Ageing and Mesothelioma Drive Lipid Accumulation and Dysfunction in Dendritic Cells and Macrophages |
| title | Ageing and Mesothelioma Drive Lipid Accumulation and Dysfunction in Dendritic Cells and Macrophages |
| title_full | Ageing and Mesothelioma Drive Lipid Accumulation and Dysfunction in Dendritic Cells and Macrophages |
| title_fullStr | Ageing and Mesothelioma Drive Lipid Accumulation and Dysfunction in Dendritic Cells and Macrophages |
| title_full_unstemmed | Ageing and Mesothelioma Drive Lipid Accumulation and Dysfunction in Dendritic Cells and Macrophages |
| title_short | Ageing and Mesothelioma Drive Lipid Accumulation and Dysfunction in Dendritic Cells and Macrophages |
| title_sort | ageing and mesothelioma drive lipid accumulation and dysfunction in dendritic cells and macrophages |
| url | http://hdl.handle.net/20.500.11937/88901 |