Does PITP dependant PtdIns-4-P production promote encystation in Giardia duodenalis?
Giardia duodenalis is a parasite responsible for intestinal infection worldwide. This study, investigates the developmental process responsible for infection, termed of encystation. Here we investigated a protein which highly-conserved across eukaryotes, yet uncharacterized in G. duodenalis, Phospha...
| Main Author: | |
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| Format: | Thesis |
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Curtin University
2020
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| Online Access: | http://hdl.handle.net/20.500.11937/88818 |
| _version_ | 1848765091489513472 |
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| author | Davis, Aleesha Jayne |
| author_facet | Davis, Aleesha Jayne |
| author_sort | Davis, Aleesha Jayne |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Giardia duodenalis is a parasite responsible for intestinal infection worldwide. This study, investigates the developmental process responsible for infection, termed of encystation. Here we investigated a protein which highly-conserved across eukaryotes, yet uncharacterized in G. duodenalis, Phosphatidylinositol Transfer Protein (PITP). We have developed a system to determine the binding activity of this protein to determine its function in the lifecycle of G. duodenalis which may aid in the identification of a novel pharmaceutical target. |
| first_indexed | 2025-11-14T11:29:44Z |
| format | Thesis |
| id | curtin-20.500.11937-88818 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:29:44Z |
| publishDate | 2020 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-888182022-06-30T07:53:11Z Does PITP dependant PtdIns-4-P production promote encystation in Giardia duodenalis? Davis, Aleesha Jayne Giardia duodenalis is a parasite responsible for intestinal infection worldwide. This study, investigates the developmental process responsible for infection, termed of encystation. Here we investigated a protein which highly-conserved across eukaryotes, yet uncharacterized in G. duodenalis, Phosphatidylinositol Transfer Protein (PITP). We have developed a system to determine the binding activity of this protein to determine its function in the lifecycle of G. duodenalis which may aid in the identification of a novel pharmaceutical target. 2020 Thesis http://hdl.handle.net/20.500.11937/88818 Curtin University fulltext |
| spellingShingle | Davis, Aleesha Jayne Does PITP dependant PtdIns-4-P production promote encystation in Giardia duodenalis? |
| title | Does PITP dependant PtdIns-4-P production promote encystation in
Giardia duodenalis? |
| title_full | Does PITP dependant PtdIns-4-P production promote encystation in
Giardia duodenalis? |
| title_fullStr | Does PITP dependant PtdIns-4-P production promote encystation in
Giardia duodenalis? |
| title_full_unstemmed | Does PITP dependant PtdIns-4-P production promote encystation in
Giardia duodenalis? |
| title_short | Does PITP dependant PtdIns-4-P production promote encystation in
Giardia duodenalis? |
| title_sort | does pitp dependant ptdins-4-p production promote encystation in
giardia duodenalis? |
| url | http://hdl.handle.net/20.500.11937/88818 |