Characterising Biomarkers of Chronic Lung Disease in Survivors of Preterm Birth

This research found preterm-born children displayed poor respiratory outcomes, with evidence of increased neutrophilic inflammation and oxidative stress, rather than the eosinophilic profile associated with “typical” childhood asthma. Additionally, metabolomic analysis showed preterm-born individual...

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Bibliographic Details
Main Author: Urs, Rhea Caroline
Format: Thesis
Published: Curtin University 2021
Online Access:http://hdl.handle.net/20.500.11937/88817
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author Urs, Rhea Caroline
author_facet Urs, Rhea Caroline
author_sort Urs, Rhea Caroline
building Curtin Institutional Repository
collection Online Access
description This research found preterm-born children displayed poor respiratory outcomes, with evidence of increased neutrophilic inflammation and oxidative stress, rather than the eosinophilic profile associated with “typical” childhood asthma. Additionally, metabolomic analysis showed preterm-born individuals have an altered metabolome from those born at term. Together this research provides insight into the contributors of chronic lung disease providing opportunities for early intervention and better lifelong respiratory outcomes in survivors of preterm birth.
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institution Curtin University Malaysia
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publishDate 2021
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spelling curtin-20.500.11937-888172024-07-30T06:44:04Z Characterising Biomarkers of Chronic Lung Disease in Survivors of Preterm Birth Urs, Rhea Caroline This research found preterm-born children displayed poor respiratory outcomes, with evidence of increased neutrophilic inflammation and oxidative stress, rather than the eosinophilic profile associated with “typical” childhood asthma. Additionally, metabolomic analysis showed preterm-born individuals have an altered metabolome from those born at term. Together this research provides insight into the contributors of chronic lung disease providing opportunities for early intervention and better lifelong respiratory outcomes in survivors of preterm birth. 2021 Thesis http://hdl.handle.net/20.500.11937/88817 Curtin University fulltext
spellingShingle Urs, Rhea Caroline
Characterising Biomarkers of Chronic Lung Disease in Survivors of Preterm Birth
title Characterising Biomarkers of Chronic Lung Disease in Survivors of Preterm Birth
title_full Characterising Biomarkers of Chronic Lung Disease in Survivors of Preterm Birth
title_fullStr Characterising Biomarkers of Chronic Lung Disease in Survivors of Preterm Birth
title_full_unstemmed Characterising Biomarkers of Chronic Lung Disease in Survivors of Preterm Birth
title_short Characterising Biomarkers of Chronic Lung Disease in Survivors of Preterm Birth
title_sort characterising biomarkers of chronic lung disease in survivors of preterm birth
url http://hdl.handle.net/20.500.11937/88817