A Bayesian inference for the penalized spline joint models of longitudinal and time-to-event data: A prior sensitivity analysis

Bayesian approaches have been used in the literature to estimate the parameters for joint models of longitudinal and time-to-event data. The main aim of this paper is to analyze the impact of prior distributions on estimating parameters in a proposed fully Bayesian analysis setting for the penalized...

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Main Authors: Thi Thu Pham, H., Pham, H., Nur, Darfiana
Format: Journal Article
Published: 2020
Online Access:http://hdl.handle.net/20.500.11937/88546
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author Thi Thu Pham, H.
Pham, H.
Nur, Darfiana
author_facet Thi Thu Pham, H.
Pham, H.
Nur, Darfiana
author_sort Thi Thu Pham, H.
building Curtin Institutional Repository
collection Online Access
description Bayesian approaches have been used in the literature to estimate the parameters for joint models of longitudinal and time-to-event data. The main aim of this paper is to analyze the impact of prior distributions on estimating parameters in a proposed fully Bayesian analysis setting for the penalized spline joint models. To achieve this aim, the joint posterior distribution of parameters in survival and longitudinal submodels is presented. The Markov chain Monte Carlo (MCMC) algorithm is then proposed, which consists of the Gibbs sampler (GS) and Metropolis Hastings (MH) algorithms to sample for the target conditional posterior distributions. The prior sensitivity analysis for the baseline hazard rate and association parameters is performed through simulation studies and a case study.
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format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T11:28:55Z
publishDate 2020
recordtype eprints
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spelling curtin-20.500.11937-885462022-06-13T04:45:34Z A Bayesian inference for the penalized spline joint models of longitudinal and time-to-event data: A prior sensitivity analysis Thi Thu Pham, H. Pham, H. Nur, Darfiana Bayesian approaches have been used in the literature to estimate the parameters for joint models of longitudinal and time-to-event data. The main aim of this paper is to analyze the impact of prior distributions on estimating parameters in a proposed fully Bayesian analysis setting for the penalized spline joint models. To achieve this aim, the joint posterior distribution of parameters in survival and longitudinal submodels is presented. The Markov chain Monte Carlo (MCMC) algorithm is then proposed, which consists of the Gibbs sampler (GS) and Metropolis Hastings (MH) algorithms to sample for the target conditional posterior distributions. The prior sensitivity analysis for the baseline hazard rate and association parameters is performed through simulation studies and a case study. 2020 Journal Article http://hdl.handle.net/20.500.11937/88546 10.1515/mcma-2020-2058 restricted
spellingShingle Thi Thu Pham, H.
Pham, H.
Nur, Darfiana
A Bayesian inference for the penalized spline joint models of longitudinal and time-to-event data: A prior sensitivity analysis
title A Bayesian inference for the penalized spline joint models of longitudinal and time-to-event data: A prior sensitivity analysis
title_full A Bayesian inference for the penalized spline joint models of longitudinal and time-to-event data: A prior sensitivity analysis
title_fullStr A Bayesian inference for the penalized spline joint models of longitudinal and time-to-event data: A prior sensitivity analysis
title_full_unstemmed A Bayesian inference for the penalized spline joint models of longitudinal and time-to-event data: A prior sensitivity analysis
title_short A Bayesian inference for the penalized spline joint models of longitudinal and time-to-event data: A prior sensitivity analysis
title_sort bayesian inference for the penalized spline joint models of longitudinal and time-to-event data: a prior sensitivity analysis
url http://hdl.handle.net/20.500.11937/88546