Investigating the structure and binding mechanism of QseM, a novel dual-target protein-inhibitor
This thesis details the structural characterisation of a novel protein, QseM, through the use of X-ray crystallography and nuclear magnetic resonance. QseM contains the uncharacterised DUF2285 domain, which, through this work, has been revealed to be a novel helix-turn-helix motif.
| Main Author: | |
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| Format: | Thesis |
| Published: |
Curtin University
2021
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| Online Access: | http://hdl.handle.net/20.500.11937/87895 |
| _version_ | 1848764946764005376 |
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| author | Hall, Drew Anthony |
| author_facet | Hall, Drew Anthony |
| author_sort | Hall, Drew Anthony |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | This thesis details the structural characterisation of a novel protein, QseM, through the use of X-ray crystallography and nuclear magnetic resonance. QseM contains the uncharacterised DUF2285 domain, which, through this work, has been revealed to be a novel helix-turn-helix motif. |
| first_indexed | 2025-11-14T11:27:26Z |
| format | Thesis |
| id | curtin-20.500.11937-87895 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:27:26Z |
| publishDate | 2021 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-878952022-02-24T06:00:57Z Investigating the structure and binding mechanism of QseM, a novel dual-target protein-inhibitor Hall, Drew Anthony This thesis details the structural characterisation of a novel protein, QseM, through the use of X-ray crystallography and nuclear magnetic resonance. QseM contains the uncharacterised DUF2285 domain, which, through this work, has been revealed to be a novel helix-turn-helix motif. 2021 Thesis http://hdl.handle.net/20.500.11937/87895 Curtin University fulltext |
| spellingShingle | Hall, Drew Anthony Investigating the structure and binding mechanism of QseM, a novel dual-target protein-inhibitor |
| title | Investigating the structure and binding mechanism of QseM,
a novel dual-target protein-inhibitor |
| title_full | Investigating the structure and binding mechanism of QseM,
a novel dual-target protein-inhibitor |
| title_fullStr | Investigating the structure and binding mechanism of QseM,
a novel dual-target protein-inhibitor |
| title_full_unstemmed | Investigating the structure and binding mechanism of QseM,
a novel dual-target protein-inhibitor |
| title_short | Investigating the structure and binding mechanism of QseM,
a novel dual-target protein-inhibitor |
| title_sort | investigating the structure and binding mechanism of qsem,
a novel dual-target protein-inhibitor |
| url | http://hdl.handle.net/20.500.11937/87895 |