Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections
In this study, resistance towards antimicrobial peptides developed rapidly in MRSA, but resistance was mitigated by controlling the environment in which the cells are treated. Resistance was not stable in a population and seemed to sensitise some cells to certain antibiotics. Antibacterial peptides...
| Main Author: | |
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| Format: | Thesis |
| Language: | English |
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Curtin University
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/870 |
| _version_ | 1848743504687136768 |
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| author | Ravensdale, Joshua Thomas |
| author_facet | Ravensdale, Joshua Thomas |
| author_sort | Ravensdale, Joshua Thomas |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | In this study, resistance towards antimicrobial peptides developed rapidly in MRSA, but resistance was mitigated by controlling the environment in which the cells are treated. Resistance was not stable in a population and seemed to sensitise some cells to certain antibiotics. Antibacterial peptides enhanced the bactericidal effectiveness of an antibacterial gauze when used in tandem with a wetting agent and lysozyme. Results from this study suggest antibacterial peptides may have clinical applications as topical therapeutics. |
| first_indexed | 2025-11-14T05:46:37Z |
| format | Thesis |
| id | curtin-20.500.11937-870 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:46:37Z |
| publishDate | 2015 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-8702017-02-20T06:40:03Z Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections Ravensdale, Joshua Thomas In this study, resistance towards antimicrobial peptides developed rapidly in MRSA, but resistance was mitigated by controlling the environment in which the cells are treated. Resistance was not stable in a population and seemed to sensitise some cells to certain antibiotics. Antibacterial peptides enhanced the bactericidal effectiveness of an antibacterial gauze when used in tandem with a wetting agent and lysozyme. Results from this study suggest antibacterial peptides may have clinical applications as topical therapeutics. 2015 Thesis http://hdl.handle.net/20.500.11937/870 en Curtin University fulltext |
| spellingShingle | Ravensdale, Joshua Thomas Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections |
| title | Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections |
| title_full | Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections |
| title_fullStr | Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections |
| title_full_unstemmed | Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections |
| title_short | Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections |
| title_sort | investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical staphylococcus aureus infections |
| url | http://hdl.handle.net/20.500.11937/870 |