Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan
Background: Globally, tuberculosis (TB) remains the leading cause of death from a single infectious disease. TB treatment outcome is an important indicator for the effectiveness of a national TB control program. This study aimed to assess treatment outcomes of TB patients and its determinants in Bat...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
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BMC
2020
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/86479 |
| _version_ | 1848764833957150720 |
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| author | Ahmad, T. Jadoon, M.A. Khan, M. Haroon Khan, M.M. Hussain, A. Musa, T.H. Waqar, M. Ejeta, E. Karami, M. Alene, Kefyalew Jin, H. Ahmad, T. |
| author_facet | Ahmad, T. Jadoon, M.A. Khan, M. Haroon Khan, M.M. Hussain, A. Musa, T.H. Waqar, M. Ejeta, E. Karami, M. Alene, Kefyalew Jin, H. Ahmad, T. |
| author_sort | Ahmad, T. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: Globally, tuberculosis (TB) remains the leading cause of death from a single infectious disease. TB treatment outcome is an important indicator for the effectiveness of a national TB control program. This study aimed to assess treatment outcomes of TB patients and its determinants in Batkhela, Khyber Pakhtunkhwa, Pakistan.
Methods: A retrospective cohort study was designed using all TB patients who were enrolled at District Head Quarter (DHQ) Hospital Batkhela, Pakistan, from January 2011 to December 2014. A binary logistic regression models were used to identify factors associated with successful TB treatment outcomes defined as the sum of cure and completed treatment.
Results: A total of 515 TB patients were registered, of which 237 (46%) were males and 278 (53.98%) females. Of all patients, 234 (45.44%) were cured and 210 (40.77%) completed treatment. The overall treatment success rate was 444 (86.21%). Age 0-20 years (adjusted odds ratio, AOR = 3.47; 95% confidence interval, CI) = 1.54-7.81; P = 0.003), smear-positive pulmonary TB (AOR) = 3.58; 95% CI = 1.89-6.78; P = < 0.001), treatment category (AOR = 4.71; 95% CI = 1.17-18.97; P = 0.029), and year of enrollment 2012 (AOR = 6.26; 95% CI = 2.52-15.59; P = < 0.001) were significantly associated with successful treatment outcome.
Conclusions: The overall treatment success rate is satisfactory but still need to be improved to achieve the international targeted treatment outcome. Type of TB, age, treatment category, and year of enrollment were significantly associated with successful treatment outcomes. |
| first_indexed | 2025-11-14T11:25:39Z |
| format | Journal Article |
| id | curtin-20.500.11937-86479 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T11:25:39Z |
| publishDate | 2020 |
| publisher | BMC |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-864792021-11-22T04:58:15Z Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan Ahmad, T. Jadoon, M.A. Khan, M. Haroon Khan, M.M. Hussain, A. Musa, T.H. Waqar, M. Ejeta, E. Karami, M. Alene, Kefyalew Jin, H. Ahmad, T. Science & Technology Life Sciences & Biomedicine Infectious Diseases Tuberculosis Treatment outcome Pakistan SHORT-COURSE DOTS PULMONARY TUBERCULOSIS DISTRICT MALAKAND POPULATION PREVALENCE STILL Background: Globally, tuberculosis (TB) remains the leading cause of death from a single infectious disease. TB treatment outcome is an important indicator for the effectiveness of a national TB control program. This study aimed to assess treatment outcomes of TB patients and its determinants in Batkhela, Khyber Pakhtunkhwa, Pakistan. Methods: A retrospective cohort study was designed using all TB patients who were enrolled at District Head Quarter (DHQ) Hospital Batkhela, Pakistan, from January 2011 to December 2014. A binary logistic regression models were used to identify factors associated with successful TB treatment outcomes defined as the sum of cure and completed treatment. Results: A total of 515 TB patients were registered, of which 237 (46%) were males and 278 (53.98%) females. Of all patients, 234 (45.44%) were cured and 210 (40.77%) completed treatment. The overall treatment success rate was 444 (86.21%). Age 0-20 years (adjusted odds ratio, AOR = 3.47; 95% confidence interval, CI) = 1.54-7.81; P = 0.003), smear-positive pulmonary TB (AOR) = 3.58; 95% CI = 1.89-6.78; P = < 0.001), treatment category (AOR = 4.71; 95% CI = 1.17-18.97; P = 0.029), and year of enrollment 2012 (AOR = 6.26; 95% CI = 2.52-15.59; P = < 0.001) were significantly associated with successful treatment outcome. Conclusions: The overall treatment success rate is satisfactory but still need to be improved to achieve the international targeted treatment outcome. Type of TB, age, treatment category, and year of enrollment were significantly associated with successful treatment outcomes. 2020 Journal Article http://hdl.handle.net/20.500.11937/86479 10.1186/s12879-020-05184-3 English http://creativecommons.org/licenses/by/4.0/ BMC fulltext |
| spellingShingle | Science & Technology Life Sciences & Biomedicine Infectious Diseases Tuberculosis Treatment outcome Pakistan SHORT-COURSE DOTS PULMONARY TUBERCULOSIS DISTRICT MALAKAND POPULATION PREVALENCE STILL Ahmad, T. Jadoon, M.A. Khan, M. Haroon Khan, M.M. Hussain, A. Musa, T.H. Waqar, M. Ejeta, E. Karami, M. Alene, Kefyalew Jin, H. Ahmad, T. Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan |
| title | Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan |
| title_full | Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan |
| title_fullStr | Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan |
| title_full_unstemmed | Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan |
| title_short | Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan |
| title_sort | treatment outcomes of patients with tuberculosis in war affected region of khyber pakhtunkhwa, pakistan |
| topic | Science & Technology Life Sciences & Biomedicine Infectious Diseases Tuberculosis Treatment outcome Pakistan SHORT-COURSE DOTS PULMONARY TUBERCULOSIS DISTRICT MALAKAND POPULATION PREVALENCE STILL |
| url | http://hdl.handle.net/20.500.11937/86479 |