Characterization of molecular interactions of small molecules with model cell membranes
Characterisation of the molecular mechanism and energetics of the interaction of small molecules with cell membranes is of the utmost biological importance to understand and optimise the action of drugs. This work describes the development, validation and application of new molecular dynamics simula...
| Main Author: | |
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| Format: | Thesis |
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Curtin University
2021
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| Online Access: | http://hdl.handle.net/20.500.11937/86447 |
| _version_ | 1848764824900599808 |
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| author | Martinotti, Carlo |
| author_facet | Martinotti, Carlo |
| author_sort | Martinotti, Carlo |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Characterisation of the molecular mechanism and energetics of the interaction of small molecules with cell membranes is of the utmost biological importance to understand and optimise the action of drugs. This work describes the development, validation and application of new molecular dynamics simulation approaches for the prediction of the interactions and binding affinity of drug-like molecules and bioactive peptides to phospholipid bilayers. |
| first_indexed | 2025-11-14T11:25:30Z |
| format | Thesis |
| id | curtin-20.500.11937-86447 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:25:30Z |
| publishDate | 2021 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-864472023-11-21T00:43:59Z Characterization of molecular interactions of small molecules with model cell membranes Martinotti, Carlo Characterisation of the molecular mechanism and energetics of the interaction of small molecules with cell membranes is of the utmost biological importance to understand and optimise the action of drugs. This work describes the development, validation and application of new molecular dynamics simulation approaches for the prediction of the interactions and binding affinity of drug-like molecules and bioactive peptides to phospholipid bilayers. 2021 Thesis http://hdl.handle.net/20.500.11937/86447 Curtin University fulltext |
| spellingShingle | Martinotti, Carlo Characterization of molecular interactions of small molecules with model cell membranes |
| title | Characterization of molecular interactions of small
molecules with model cell membranes |
| title_full | Characterization of molecular interactions of small
molecules with model cell membranes |
| title_fullStr | Characterization of molecular interactions of small
molecules with model cell membranes |
| title_full_unstemmed | Characterization of molecular interactions of small
molecules with model cell membranes |
| title_short | Characterization of molecular interactions of small
molecules with model cell membranes |
| title_sort | characterization of molecular interactions of small
molecules with model cell membranes |
| url | http://hdl.handle.net/20.500.11937/86447 |