Imaging Cannabinoid Receptors: A Brief Collection of Covalent and Fluorescent Probes for CB1 and CB2 Receptors

QR Code

Imaging Cannabinoid Receptors: A Brief Collection of Covalent and Fluorescent Probes for CB1 and CB2 Receptors

There has been an expanding public interest towards the notion that modulation of the sophisticated endocannabinoid system can lead to various therapeutic benefits that are yet to be fully explored. In recent years, the drug discovery paradigm in this field has been largely based on the development...

Full description

Bibliographic Details
Main Authors:	Hamilton, A.J., Payne, Alan, Mocerino, Mauro, Gunosewoyo, Hendra
Format:	Journal Article
Language:	English
Published:	CSIRO PUBLISHING 2021
Subjects:	Science & Technology Physical Sciences Chemistry, Multidisciplinary Chemistry imaging agents cannabinoids fluorescent probes electrophilic probes photoaffinity labelling synthetic cannabinoids cannabinoid receptor ligand-assisted protein structure AFFINITY IRREVERSIBLE PROBE PROTEIN-COUPLED RECEPTORS ENDOCANNABINOID SYSTEM LIGAND-BINDING MOLECULAR CHARACTERIZATION ALLOSTERIC MODULATION TYPE-2 RECEPTOR PHARMACOLOGICAL EVALUATION INTERACTION LANDSCAPE SELECTIVE ANTAGONIST
Online Access:	http://purl.org/au-research/grants/arc/DE160100482 http://hdl.handle.net/20.500.11937/86277

Similar Items

Investigating the molecular basis of biased signalling at cannabinoid receptors
by: Dennis, Morgan Jane
Published: (2023)

Investigating ligand-directed signalling at the cannabinoid receptor 2
by: Hourani, Wafa
Published: (2019)

Endocannabinoid metabolism and peroxisome proliferator-activated receptor signalling
by: Dionisi, Mauro
Published: (2010)

Small molecule-based fluorescent probes as tool compounds for chemokine receptors CXCR4 and ACKR3
by: Dekkers, Sebastian
Published: (2019)

Structural exploration of cannabinoid receptors using computational methods
by: Murali, Lahari
Published: (2020)

Δ9-tetrahydrocannabinol reverses TNFα-induced increase in airway epithelial cell permeability through CB2 receptors
by: Shang, Valerie C.M., et al.
Published: (2016)

Illuminating the life of the adenosine receptors: development and application of subtype-selective fluorescent probes for the study of the human A1 and A2A adenosine receptors in living cells
by: Comeo, Eleonora
Published: (2022)

Fluorescent cannabinoids: Stratagies towards the synthesis of fluorescently labelled CB2 receptor ligands
by: Yates, Andrew Stephen
Published: (2005)

An investigation into the pharmacological effects of phytocannabinoids and endocannaboids in human mesenteric arteries
by: Stanley, Christopher Peter
Published: (2013)

Biased allosteric modulators of metabotropic glutamate receptor 5
by: Sengmany, Kathy
Published: (2018)

Effect of cannabinoid receptor ligands on microglial cell functions
by: Hassan, Samia
Published: (2013)

An evaluation of DREADD receptor pharmacology in recombinant cells and astrocytes
by: Carpenter, Jessica
Published: (2020)

Measuring ligand concentration where it matters: Assessing the “micro pharmacokinetic/pharmacodynamics” of adenosine receptor ligands
by: Lochray, Jack
Published: (2022)

Anti-nociceptive and desensitizing effects of olvanil on capsaicin-induced thermal hyperalgesia in the rat
by: Alsalem, Mohammad, et al.
Published: (2016)

Effects of the cannabinoid CB1 agonist ACEA on salicylate ototoxicity, hyperacusis and tinnitus in guinea pigs
by: Berger, Joel I., et al.
Published: (2017)

Neurotherapeutic potential of synthetic cannabinoid receptor agonist, WIN55,212-2 on Aluminium chloride and D-galactose- induced cognitive impairments in male Wistar rats
by: Onesimus, Mahdi
Published: (2021)

The effects of cannabinoids on insulin secretion
by: Anderson, Richard L.
Published: (2011)

Universal sensors for identifying use-dependent intracellular allosteric modulators of G protein coupled receptors
by: Farmer, James
Published: (2024)

Design, Synthesis, and Development of Novel Fluorescently Labelled Allosteric Probes for the Human Beta2-Adrenoceptor
by: Tuzer, Cemre
Published: (2023)

Design, Synthesis, and Evaluation of New P2Y2 Receptor Antagonists and Fluorescent Ligands
by: Knight, Rebecca
Published: (2025)

Patterns of synthetic cannabinoid use in Australia
by: Barratt, Monica, et al.
Published: (2012)

Delivery of cannabinoids to specific anatomical regions of the brain following oral administration to reach the site of action for glioblastoma multiforme and multiple sclerosis
by: Brookes, Alice
Published: (2023)

The use of fluorescence correlation spectroscopy to characterize the molecular mobility of fluorescently labelled G protein-coupled receptors
by: Kilpatrick, Laura E., et al.
Published: (2016)

An investigation into the metabolic and cardiovascular effects of phytocannabinoids using in vivo and in vitro techniques
by: Jadoon, K.A.
Published: (2016)

Optimisation of Peptide Linker-based Fluorescent Ligands for the Histamine H1 Receptor
by: Kok, Zhi Yuan
Published: (2020)

The use of cannabinoids in colitis: a systematic review and meta-analysis
by: Couch, Daniel G., et al.
Published: (2018)

Modulation of mu-opioid receptor dynamics at the plasma membrane and its implications for signalling and trafficking
by: Underwood, Owen George
Published: (2024)

The endocannabinoid, anandamide, induces cannabinoid receptor-independent cell death in renal proximal tubule cells
by: Schlosser, Monika, et al.
Published: (2017)

Histidine146 of Human Serum Albumin Plays a Prominent Role at the Interface of Subdomains IA and IIA in Allosteric Ligand Binding
by: Kaneko, K., et al.
Published: (2011)

Cannabinoids in experimental stroke: a systematic review and meta-analysis
by: England, Timothy J., et al.
Published: (2015)

Contribution of intestinal lymphatic transport to the antiproliferative effect of delta-9-tetrahydrocannabinol
by: Wong, Jonathan Chi Man
Published: (2017)

Cell adhesion: stochastic receptor-ligand binding under force
by: Bagdasar, Ovidiu
Published: (2011)

Allosteric interactions at adenosine A1 and A3 receptors: new insights into the role of small molecules and receptor dimerization
by: Hill, Stephen J., et al.
Published: (2014)

A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells
by: Arruda, Maria Augusta, et al.
Published: (2017)

Use of a new proximity assay (NanoBRET) to investigate the ligand binding characteristics of three fluorescent ligands to the human β1-adrenoceptor expressed in HEK-293 cells
by: Soave, Mark, et al.
Published: (2016)

The actions of cannabidiol and palmitoylethanolamide on inflammation and permeability of the gut
by: Couch, Daniel
Published: (2018)

Sensory gating and its modulation by cannabinoids: electrophysiological, computational and mathematical analysis
by: Zachariou, Margarita, et al.
Published: (2008)

Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors
by: van der Westhuizen, Emma T., et al.
Published: (2018)

Real-time analysis of the binding of fluorescent VEGF₁₆₅a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes
by: Kilpatrick, Laura E., et al.
Published: (2017)

Identification of a Cyanine-dye labeled peptidic ligand for Y₁R and Y₄R, based upon the Neuropeptide Y C-terminal analogue, BVD-15
by: Liu, Mengjie, et al.
Published: (2016)

Cannot write session to /tmp/vufind_sessions/sess_nnchspkeou5v5s2ij5k23j2okv