Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa
This study aimed to identify alcohol use patterns associated with viral non-suppression among women living with HIV (WLWH) and the extent to which adherence mediated these relationships. Baseline data on covariates, alcohol consumption, ART adherence, and viral load were collected from 608 WLWH on A...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Journal Article |
| Language: | English |
| Published: |
SPRINGER/PLENUM PUBLISHERS
2021
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/86256 |
| _version_ | 1848764799969656832 |
|---|---|
| author | Myers-Franchi, Bronwyn Lombard, C. Joska, J.A. Abdullah, F. Naledi, T. Lund, C. Petersen Williams, P. Stein, D.J. Sorsdahl, K.R. |
| author_facet | Myers-Franchi, Bronwyn Lombard, C. Joska, J.A. Abdullah, F. Naledi, T. Lund, C. Petersen Williams, P. Stein, D.J. Sorsdahl, K.R. |
| author_sort | Myers-Franchi, Bronwyn |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | This study aimed to identify alcohol use patterns associated with viral non-suppression among women living with HIV (WLWH) and the extent to which adherence mediated these relationships. Baseline data on covariates, alcohol consumption, ART adherence, and viral load were collected from 608 WLWH on ART living in the Western Cape, South Africa. We defined three consumption patterns: no/light drinking (drinking ≤ 1/week and ≤ 4 drinks/occasion), occasional heavy episodic drinking (HED) (drinking > 1 and ≤ 2/week and ≥ 5 drinks/occasion) and frequent HED (drinking ≥ 3 times/week and ≥ 5 drinks/occasion). In multivariable analyses, occasional HED (OR 3.07, 95% CI 1.78–5.30) and frequent HED (OR 7.11, 95% CI 4.24–11.92) were associated with suboptimal adherence. Frequent HED was associated with viral non-suppression (OR 2.08, 95% CI 1.30–3.28). Suboptimal adherence partially mediated the relationship between frequent HED and viral non-suppression. Findings suggest a direct relationship between frequency of HED and viral suppression. Given the mediating effects of adherence on this relationship, alcohol interventions should be tailored to frequency of HED while also addressing adherence. |
| first_indexed | 2025-11-14T11:25:06Z |
| format | Journal Article |
| id | curtin-20.500.11937-86256 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T11:25:06Z |
| publishDate | 2021 |
| publisher | SPRINGER/PLENUM PUBLISHERS |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-862562021-11-11T01:22:08Z Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa Myers-Franchi, Bronwyn Lombard, C. Joska, J.A. Abdullah, F. Naledi, T. Lund, C. Petersen Williams, P. Stein, D.J. Sorsdahl, K.R. Science & Technology Social Sciences Life Sciences & Biomedicine Public, Environmental & Occupational Health Social Sciences, Biomedical Biomedical Social Sciences Women Alcohol Viral load suppression Mediators HIV South Africa ANTIRETROVIRAL THERAPY USE DISORDERS TREATMENT OUTCOMES ADHERENCE DRINKING HEALTH CARE CONSUMPTION INFECTION KNOWLEDGE This study aimed to identify alcohol use patterns associated with viral non-suppression among women living with HIV (WLWH) and the extent to which adherence mediated these relationships. Baseline data on covariates, alcohol consumption, ART adherence, and viral load were collected from 608 WLWH on ART living in the Western Cape, South Africa. We defined three consumption patterns: no/light drinking (drinking ≤ 1/week and ≤ 4 drinks/occasion), occasional heavy episodic drinking (HED) (drinking > 1 and ≤ 2/week and ≥ 5 drinks/occasion) and frequent HED (drinking ≥ 3 times/week and ≥ 5 drinks/occasion). In multivariable analyses, occasional HED (OR 3.07, 95% CI 1.78–5.30) and frequent HED (OR 7.11, 95% CI 4.24–11.92) were associated with suboptimal adherence. Frequent HED was associated with viral non-suppression (OR 2.08, 95% CI 1.30–3.28). Suboptimal adherence partially mediated the relationship between frequent HED and viral non-suppression. Findings suggest a direct relationship between frequency of HED and viral suppression. Given the mediating effects of adherence on this relationship, alcohol interventions should be tailored to frequency of HED while also addressing adherence. 2021 Journal Article http://hdl.handle.net/20.500.11937/86256 10.1007/s10461-021-03263-3 English http://creativecommons.org/licenses/by/4.0/ SPRINGER/PLENUM PUBLISHERS fulltext |
| spellingShingle | Science & Technology Social Sciences Life Sciences & Biomedicine Public, Environmental & Occupational Health Social Sciences, Biomedical Biomedical Social Sciences Women Alcohol Viral load suppression Mediators HIV South Africa ANTIRETROVIRAL THERAPY USE DISORDERS TREATMENT OUTCOMES ADHERENCE DRINKING HEALTH CARE CONSUMPTION INFECTION KNOWLEDGE Myers-Franchi, Bronwyn Lombard, C. Joska, J.A. Abdullah, F. Naledi, T. Lund, C. Petersen Williams, P. Stein, D.J. Sorsdahl, K.R. Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa |
| title | Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa |
| title_full | Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa |
| title_fullStr | Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa |
| title_full_unstemmed | Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa |
| title_short | Associations Between Patterns of Alcohol Use and Viral Load Suppression Amongst Women Living with HIV in South Africa |
| title_sort | associations between patterns of alcohol use and viral load suppression amongst women living with hiv in south africa |
| topic | Science & Technology Social Sciences Life Sciences & Biomedicine Public, Environmental & Occupational Health Social Sciences, Biomedical Biomedical Social Sciences Women Alcohol Viral load suppression Mediators HIV South Africa ANTIRETROVIRAL THERAPY USE DISORDERS TREATMENT OUTCOMES ADHERENCE DRINKING HEALTH CARE CONSUMPTION INFECTION KNOWLEDGE |
| url | http://hdl.handle.net/20.500.11937/86256 |