Design, synthesis and application of luminescent metal tetrazolato complexes in optical imaging
Fundamental investigation into a series of Re(I) tetrazolato complexes as optical imaging agents provided insight into how structural modifications influence their chemical, photophysical and biological properties. Modulation of the complexes through protonation and methylation of the tetrazolato li...
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| Format: | Thesis |
| Language: | English |
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Curtin University
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/852 |
| _version_ | 1848743499458936832 |
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| author | Werrett, Melissa Vivienne |
| author_facet | Werrett, Melissa Vivienne |
| author_sort | Werrett, Melissa Vivienne |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Fundamental investigation into a series of Re(I) tetrazolato complexes as optical imaging agents provided insight into how structural modifications influence their chemical, photophysical and biological properties. Modulation of the complexes through protonation and methylation of the tetrazolato ligand led to improved photophysical performance. Functionalisation at the diimine ligand revealed photophysical output is not appreciably altered. Live cell imaging with the Re(I) complexes showed HeLa cell uptake with perinuclear localisation. |
| first_indexed | 2025-11-14T05:46:33Z |
| format | Thesis |
| id | curtin-20.500.11937-852 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T05:46:33Z |
| publishDate | 2014 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-8522017-02-20T06:41:34Z Design, synthesis and application of luminescent metal tetrazolato complexes in optical imaging Werrett, Melissa Vivienne Fundamental investigation into a series of Re(I) tetrazolato complexes as optical imaging agents provided insight into how structural modifications influence their chemical, photophysical and biological properties. Modulation of the complexes through protonation and methylation of the tetrazolato ligand led to improved photophysical performance. Functionalisation at the diimine ligand revealed photophysical output is not appreciably altered. Live cell imaging with the Re(I) complexes showed HeLa cell uptake with perinuclear localisation. 2014 Thesis http://hdl.handle.net/20.500.11937/852 en Curtin University fulltext |
| spellingShingle | Werrett, Melissa Vivienne Design, synthesis and application of luminescent metal tetrazolato complexes in optical imaging |
| title | Design, synthesis and application of luminescent metal tetrazolato complexes in optical imaging |
| title_full | Design, synthesis and application of luminescent metal tetrazolato complexes in optical imaging |
| title_fullStr | Design, synthesis and application of luminescent metal tetrazolato complexes in optical imaging |
| title_full_unstemmed | Design, synthesis and application of luminescent metal tetrazolato complexes in optical imaging |
| title_short | Design, synthesis and application of luminescent metal tetrazolato complexes in optical imaging |
| title_sort | design, synthesis and application of luminescent metal tetrazolato complexes in optical imaging |
| url | http://hdl.handle.net/20.500.11937/852 |