TWEAK/Fn14 signalling promotes cholangiocarcinoma niche formation and progression

TWEAK/Fn14 signalling promotes cholangiocarcinoma niche formation and progression

Background & Aims: Cholangiocarcinoma (CCA) is a cancer of the hepatic bile ducts that is rarely resectable and is associated with poor prognosis. Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) is known to signal via its receptor fibroblast growth factor-inducible 14 (Fn14) and in...

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Bibliographic Details
Main Authors: Dwyer, Ben, Jarman, E.J., Gogoi-Tiwari, Jully, Ferreira-Gonzalez, S., Boulter, L., Guest, R.V., Kendall, T.J., Kurian, D., Kilpatrick, A.M., Robson, A.J., O'Duibhir, E., Man, T.Y., Campana, L., Starkey Lewis, P.J., Wigmore, S.J., Olynyk, John, Ramm, G.A., Tirnitz-Parker, Nina, Forbes, S.J.
Format: Journal Article
Language:English
Published: ELSEVIER 2021
Subjects:
Science & Technology
Life Sciences & Biomedicine
Gastroenterology & Hepatology
Cholangiocarcinoma
Liver cancer
TWEAK
Fn14
Tumour-associated macrophage
Cancer-associated fibroblast
Online Access:http://purl.org/au-research/grants/nhmrc/1031330
http://hdl.handle.net/20.500.11937/84925

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