Investigating Changes to the Post Translational Modification Status of Key Components of the ER Translocation Machinery in Saccharomyces Cerevisiae
Dysfunction of the endoplasmic reticulum is commonly observed in disease, however, the exact nature in which this manifests requires further investigation. We have examined the role post translational modifications have in regulating multiple aspects of cellular biology using the model organism, Sac...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Published: |
Curtin University
2019
|
| Online Access: | http://hdl.handle.net/20.500.11937/82125 |
| _version_ | 1848764476993568768 |
|---|---|
| author | Stevens, Kofi Lewis Paul |
| author_facet | Stevens, Kofi Lewis Paul |
| author_sort | Stevens, Kofi Lewis Paul |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Dysfunction of the endoplasmic reticulum is commonly observed in disease, however, the exact nature in which this manifests requires further investigation. We have examined the role post translational modifications have in regulating multiple aspects of cellular biology using the model organism, Saccharomyces cerevisiae. This work highlights the complex nature of the endoplasmic reticulum, elucidating novel mechanisms whereby phosphorylation and glycosylation are able to modulate activity in response to changes in the cellular environment. |
| first_indexed | 2025-11-14T11:19:58Z |
| format | Thesis |
| id | curtin-20.500.11937-82125 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:19:58Z |
| publishDate | 2019 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-821252020-12-15T04:30:40Z Investigating Changes to the Post Translational Modification Status of Key Components of the ER Translocation Machinery in Saccharomyces Cerevisiae Stevens, Kofi Lewis Paul Dysfunction of the endoplasmic reticulum is commonly observed in disease, however, the exact nature in which this manifests requires further investigation. We have examined the role post translational modifications have in regulating multiple aspects of cellular biology using the model organism, Saccharomyces cerevisiae. This work highlights the complex nature of the endoplasmic reticulum, elucidating novel mechanisms whereby phosphorylation and glycosylation are able to modulate activity in response to changes in the cellular environment. 2019 Thesis http://hdl.handle.net/20.500.11937/82125 Curtin University fulltext |
| spellingShingle | Stevens, Kofi Lewis Paul Investigating Changes to the Post Translational Modification Status of Key Components of the ER Translocation Machinery in Saccharomyces Cerevisiae |
| title | Investigating Changes to the Post Translational Modification Status of Key Components of the ER Translocation Machinery in Saccharomyces Cerevisiae |
| title_full | Investigating Changes to the Post Translational Modification Status of Key Components of the ER Translocation Machinery in Saccharomyces Cerevisiae |
| title_fullStr | Investigating Changes to the Post Translational Modification Status of Key Components of the ER Translocation Machinery in Saccharomyces Cerevisiae |
| title_full_unstemmed | Investigating Changes to the Post Translational Modification Status of Key Components of the ER Translocation Machinery in Saccharomyces Cerevisiae |
| title_short | Investigating Changes to the Post Translational Modification Status of Key Components of the ER Translocation Machinery in Saccharomyces Cerevisiae |
| title_sort | investigating changes to the post translational modification status of key components of the er translocation machinery in saccharomyces cerevisiae |
| url | http://hdl.handle.net/20.500.11937/82125 |