Innovative platforms for oral microencapsulation formulation and drug analytical techniques for anti-diabetics
This thesis is divided into two main sections. The first section is about developing of silicon-based pharmaceutical platform that was used to encapsulate an anti-diabetic agent (metformin). These developed microcapsules were then characterised in terms of drug content, encapsulation efficiency, flo...
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| Format: | Thesis |
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Curtin University
2020
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| Online Access: | http://hdl.handle.net/20.500.11937/81966 |
| Summary: | This thesis is divided into two main sections. The first section is about developing of silicon-based pharmaceutical platform that was used to encapsulate an anti-diabetic agent (metformin). These developed microcapsules were then characterised in terms of drug content, encapsulation efficiency, flow properties and microscopical examination. The second section is about development and validation of a new HPLC analytical method for the detection and quantification of metformin and two other anti-diabetic agents that belong to sulfonylureas. |
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