Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode

Palladium nanoparticle-loaded carbon nanofibers (Pd/CNFs) were prepared by electrospinning and subsequent thermal treatment processes. Pd/CNFs modified carbon paste electrode (Pd/CNF-CPE) displayed excellent electrochemical catalytic activities towards dopamine (DA), uric acid (UA) and ascorbic acid...

Full description

Bibliographic Details
Main Authors: Huang, J., Liu, Yang, Hou, H., You, T.
Format: Journal Article
Published: Elsevier BV 2008
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/8194
_version_ 1848745583818309632
author Huang, J.
Liu, Yang
Hou, H.
You, T.
author_facet Huang, J.
Liu, Yang
Hou, H.
You, T.
author_sort Huang, J.
building Curtin Institutional Repository
collection Online Access
description Palladium nanoparticle-loaded carbon nanofibers (Pd/CNFs) were prepared by electrospinning and subsequent thermal treatment processes. Pd/CNFs modified carbon paste electrode (Pd/CNF-CPE) displayed excellent electrochemical catalytic activities towards dopamine (DA), uric acid (UA) and ascorbic acid (AA). The oxidation overpotentials of DA, UA and AA were decreased significantly compared with those obtained at the bare CPE. Differential pulse voltammetry was used for the simultaneous determination of DA, UA and AA in their ternary mixture. The peak separation between UA and DA, DA and AA was 148 mV and 244 mV, respectively. The calibration curves for DA, UA and AA were obtained in the range of 0.5–160 μM, 2–200 μM, and 0.05–4 mM, respectively. The lowest detection limits (S/N = 3) were 0.2 μM, 0.7 μM and 15 μM for DA, UA and AA, respectively. With good selectively and sensitivity, the present method was applied to the determination of DA in injectable medicine and UA in urine sample.
first_indexed 2025-11-14T06:19:40Z
format Journal Article
id curtin-20.500.11937-8194
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T06:19:40Z
publishDate 2008
publisher Elsevier BV
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-81942017-09-13T14:34:29Z Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode Huang, J. Liu, Yang Hou, H. You, T. Simultaneous determination Dopamine Electrospinning Pd nanoparticle-loaded carbon nanofiber Ascorbic acid Uric acid Palladium nanoparticle-loaded carbon nanofibers (Pd/CNFs) were prepared by electrospinning and subsequent thermal treatment processes. Pd/CNFs modified carbon paste electrode (Pd/CNF-CPE) displayed excellent electrochemical catalytic activities towards dopamine (DA), uric acid (UA) and ascorbic acid (AA). The oxidation overpotentials of DA, UA and AA were decreased significantly compared with those obtained at the bare CPE. Differential pulse voltammetry was used for the simultaneous determination of DA, UA and AA in their ternary mixture. The peak separation between UA and DA, DA and AA was 148 mV and 244 mV, respectively. The calibration curves for DA, UA and AA were obtained in the range of 0.5–160 μM, 2–200 μM, and 0.05–4 mM, respectively. The lowest detection limits (S/N = 3) were 0.2 μM, 0.7 μM and 15 μM for DA, UA and AA, respectively. With good selectively and sensitivity, the present method was applied to the determination of DA in injectable medicine and UA in urine sample. 2008 Journal Article http://hdl.handle.net/20.500.11937/8194 10.1016/j.bios.2008.06.011 Elsevier BV restricted
spellingShingle Simultaneous determination
Dopamine
Electrospinning
Pd nanoparticle-loaded carbon nanofiber
Ascorbic acid
Uric acid
Huang, J.
Liu, Yang
Hou, H.
You, T.
Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode
title Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode
title_full Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode
title_fullStr Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode
title_full_unstemmed Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode
title_short Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode
title_sort simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode
topic Simultaneous determination
Dopamine
Electrospinning
Pd nanoparticle-loaded carbon nanofiber
Ascorbic acid
Uric acid
url http://hdl.handle.net/20.500.11937/8194