Syringomyelia: A review of the biomechanics
Syringomyelia is a neurological disorder caused by the development of one or more macroscopic fluid-filled cavities in the spinal cord. While the aetiology remains uncertain, hydrodynamics appear to play a role. This has led to the involvement of engineers, who have modelled the system in silico and...
| Main Authors: | , , , |
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| Format: | Journal Article |
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Elsevier Ltd.
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/8193 |
| _version_ | 1848745583573991424 |
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| author | Elliott, Novak Bertram, C. Martin, B. Brodbelt, A. |
| author_facet | Elliott, Novak Bertram, C. Martin, B. Brodbelt, A. |
| author_sort | Elliott, Novak |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Syringomyelia is a neurological disorder caused by the development of one or more macroscopic fluid-filled cavities in the spinal cord. While the aetiology remains uncertain, hydrodynamics appear to play a role. This has led to the involvement of engineers, who have modelled the system in silico and on the bench. In the process, hypotheses from the neurosurgical literature have been tested, and others generated, while aspects of the system mechanics have been clarified. The spinal cord is surrounded by cerebrospinal fluid (CSF) which is subject both to the periodic excitation of CSF expelled from the head with each heartbeat, and to intermittent larger transients from cough, sneeze, etc., via vertebral veins. The resulting pulsatile flow and pressure wave propagation, and their possible effects on cord cavities and cord stresses, have been elucidated. These engineering contributions are here reviewed for the first time. |
| first_indexed | 2025-11-14T06:19:40Z |
| format | Journal Article |
| id | curtin-20.500.11937-8193 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T06:19:40Z |
| publishDate | 2013 |
| publisher | Elsevier Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-81932019-02-19T05:35:29Z Syringomyelia: A review of the biomechanics Elliott, Novak Bertram, C. Martin, B. Brodbelt, A. Fluid–structure interaction Chiari malformation Cerebrospinal fluid Spinal cord Spinal arachnoiditis Wave propagation Syringomyelia is a neurological disorder caused by the development of one or more macroscopic fluid-filled cavities in the spinal cord. While the aetiology remains uncertain, hydrodynamics appear to play a role. This has led to the involvement of engineers, who have modelled the system in silico and on the bench. In the process, hypotheses from the neurosurgical literature have been tested, and others generated, while aspects of the system mechanics have been clarified. The spinal cord is surrounded by cerebrospinal fluid (CSF) which is subject both to the periodic excitation of CSF expelled from the head with each heartbeat, and to intermittent larger transients from cough, sneeze, etc., via vertebral veins. The resulting pulsatile flow and pressure wave propagation, and their possible effects on cord cavities and cord stresses, have been elucidated. These engineering contributions are here reviewed for the first time. 2013 Journal Article http://hdl.handle.net/20.500.11937/8193 10.1016/j.jfluidstructs.2013.01.010 Elsevier Ltd. fulltext |
| spellingShingle | Fluid–structure interaction Chiari malformation Cerebrospinal fluid Spinal cord Spinal arachnoiditis Wave propagation Elliott, Novak Bertram, C. Martin, B. Brodbelt, A. Syringomyelia: A review of the biomechanics |
| title | Syringomyelia: A review of the biomechanics |
| title_full | Syringomyelia: A review of the biomechanics |
| title_fullStr | Syringomyelia: A review of the biomechanics |
| title_full_unstemmed | Syringomyelia: A review of the biomechanics |
| title_short | Syringomyelia: A review of the biomechanics |
| title_sort | syringomyelia: a review of the biomechanics |
| topic | Fluid–structure interaction Chiari malformation Cerebrospinal fluid Spinal cord Spinal arachnoiditis Wave propagation |
| url | http://hdl.handle.net/20.500.11937/8193 |