A RNA interference screen identifies the protein phosphatase 2A subunit PR55γ as a stress-sensitive inhibitor of c-SRC

QR Code

A RNA interference screen identifies the protein phosphatase 2A subunit PR55γ as a stress-sensitive inhibitor of c-SRC

© 2007 Eichhorn et al. Protein Phosphatase type 2A (PP2A) represents a family of holoenzyme complexes with diverse biological activities. Specific holoenzyme complexes are thought to be deregulated during oncogenic transformation and oncogeneinduced signaling. Since most studies on the role of...

Full description

Bibliographic Details
Main Authors:	Eichhorn, Pieter, Creyghton, M.P., Wilhelmsen, K., Van Dam, H., Bernards, R.
Format:	Journal Article
Language:	English
Published:	PUBLIC LIBRARY SCIENCE 2007
Subjects:	Science & Technology Life Sciences & Biomedicine Genetics & Heredity GROWTH-FACTOR RECEPTOR N-TERMINAL KINASE ADENOVIRUS E4ORF4 PROTEIN MIDDLE TUMOR-ANTIGEN OKADAIC ACID BREAST-CANCER SERINE/THREONINE PHOSPHATASE SIGNAL-TRANSDUCTION CSF-1 RECEPTOR CELL-GROWTH
Online Access:	http://hdl.handle.net/20.500.11937/81903

Similar Items

Effects of postbiotic and inulin supplements on growth performance, gut morphology, gene expression and fecal characteristics of broiler chicken
by: Karrem, Karwan Yaseen
Published: (2016)

Biological significance of human epidermal growth factor receptor 2 (HER2) in breast cancer: effect of oestrogen receptor
by: Ahmad, Dena Akram Jerjees
Published: (2016)

Supplementation of postbiotic RG14 in post-weaning dorper lambs to enhance growth performance, gut health and immunity
by: Wan Ibrahim, Wan Ahmad Izuddin
Published: (2018)

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma
by: De Smedt, Renate, et al.
Published: (2020)

Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep
by: Hyatt, M.A., et al.
Published: (2007)

Discovery of AZD-2098 and AZD-1678, two potent and bioavailable CCR4 receptor antagonists
by: Kindon, Nicholas, et al.
Published: (2017)

Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment
by: Nettleship, Joanne E., et al.
Published: (2013)

Translational control of epidermal growth factor receptor in neurodegenerative diseases
by: Smalley, Daniel. S.
Published: (2017)

A Potential Effect of Cordycepin on the Feedback between Polyadenylation and PI3K/Akt/mTOR Signalling
by: Lawrence, Steven
Published: (2023)

The mannose receptor negatively modulates the Toll-like receptor 4–aryl hydrocarbon receptor–indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization
by: Salazar, Fabián, et al.
Published: (2016)

Molecular characterization and genomic organization of fowl adenovirus isolates of Malaysia
by: Mohd Ayob, Juliana
Published: (2014)

Development of a live attenuated vaccine against fowl adenovirus by mutating fiber gene using crispr –CAS9 technology
by: Salisu, Ahmed
Published: (2020)

Solanum okadae - A wild diploid potato species with the potential to improve cultivated potato
by: Hundare, Amar
Published: (2023)

A kainate receptor GluK4 deletion, protective against bipolar disorder, is associated with enhanced cognitive performance across diagnoses in the TwinsUK cohort
by: Koromina, Maria, et al.
Published: (2018)

DEF6, a novel substrate for the tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies
by: Hey, Fiona, et al.

Translational control of Human Epidermal Growth Factor Receptors, HER2 and HER4 in response to cellular stresses in breast cancer cells
by: Edwards, Arnelle
Published: (2023)

A Structural Study on the Specificity of F1 Protease
by: Muhamad, Azira
Published: (2005)

Role of D1 receptor antagonism in contextual fear learning and memory
by: Heath, Florence
Published: (2015)

Functional studies of insecticides and acaricides acting on ligand-gated ion channels
by: Iqbal, Sofia
Published: (2019)

Investigating the molecular basis of biased signalling at cannabinoid receptors
by: Dennis, Morgan Jane
Published: (2023)

Using super resolution microscopy to investigate the role of actin in adenosine receptor organisation
by: Garlick, Evelyn
Published: (2023)

Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors
by: Sykes, David A., et al.
Published: (2017)

The role of indoleamine 2,3-dioxygenase in modulating allergic responses
by: Salazar, F.
Published: (2016)

Inhibition of mammalian nicotinic acetylcholine receptors by philanthotoxin analogues is strongly influenced by subunit composition
by: Kachel, Hamid Saeid
Published: (2015)

Leukotriene B4 receptor locus gene characterisation and association studies in asthma
by: Tulah, Asif S., et al.
Published: (2012)

The growing story of (ARABIDOPSIS) CRINKLY 4
by: Czyzewicz, Nathan, et al.
Published: (2016)

Effect of osmotic stress on the expression of TRPV4 and BKCa channels and possible interaction with ERK1/2 and p38 in cultured equine chondrocytes
by: Hdud, Ismail M., et al.
Published: (2014)

Effects of NAD at purine receptors in isolated blood vessels
by: Alefishat, Eman, et al.
Published: (2015)

Medicinal Chemistry & Chemical Biology Approaches to Investigate Prospective Treatments for CNS Diseases: Dopamine D1 Receptor Positive Allosteric Modulators, Dopamine D2 Receptor Positive & Negative Allosteric Modulators, Dopamine D2 Receptor-Ligand Kinetics
by: Fyfe, Tim
Published: (2019)

Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model
by: Ivell, Richard, et al.
Published: (2014)

Exposure to non-kin females rapidly affects testicular morphology in non-reproductive male Damaraland mole-rats
by: Nice, P., et al.
Published: (2010)

From a4ß2 Nicotinic Ligands to the Discovery of σ1 Receptor Ligands: Pharmacophore Analysis and Rational Design
by: Yu, L., et al.
Published: (2012)

Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα
by: Karwad, Mustafa A., et al.
Published: (2016)

The SEISICAT study: a pilot study assessing 1 efficacy and safety of spironolactone in cats with congestive heart failure secondary to cardiomyopathy
by: James, Rachel, et al.
Published: (2018)

Development of novel therapeutic agents designed to enhance insulin secretion through activation of the trace amine-associated receptor 1 (TAAR1)
by: Lenham, Rhianna
Published: (2025)

Investigating the SUMOylation and transcriptional regulation of Nurr1 and the splice variant Nurr-1a
by: Edey, Jade
Published: (2023)

Comparison of fecal hormone extraction methods and analysis on reproductive hormones in female Malayan tapirs
by: Ruslan, Muhammad Najib
Published: (2018)

Response of concentrate supplementation on ovulation rate and progesterone receptor gene in goats
by: Mohammed, Nur Hafizah
Published: (2018)

Development of live attenuated fowl adenovirus isolate of Malaysia for vaccine production
by: Mohamed Sohaimi, Norfitriah
Published: (2017)

Selective inhibition of tropomyosin-receptor-kinase A (TrkA) reduces pain and joint damage in two rat models of inflammatory arthritis
by: Ashraf, Sadaf, et al.
Published: (2016)