OTUD4 enhances TGFβ signalling through regulation of the TGFβ receptor complex

QR Code

OTUD4 enhances TGFβ signalling through regulation of the TGFβ receptor complex

© 2020, The Author(s). Systematic control of the transforming growth factor-β (TGFβ) pathway is essential to keep the amplitude and the intensity of downstream signalling at appropriate levels. Ubiquitination plays a crucial role in the general regulation of this pathway. Here we identify the deubiq...

Full description

Bibliographic Details
Main Authors:	Jaynes, P.W., Iyengar, P.V., Lui, S.K.L., Tan, T.Z., Vasilevski, Natali, Wright, Sarah Christine Elizabeth, Verdile, Giuseppe, Jeyasekharan, A.D., Eichhorn, Pieter
Format:	Journal Article
Language:	English
Published:	2020
Online Access:	http://hdl.handle.net/20.500.11937/81588

Similar Items

Response to: USP26 regulates TGF-β signalling by deubiquitinating and stabilizing SMAD7; not applicable in glioblastoma
by: Kit Leng Lui, S., et al.
Published: (2020)

c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression
by: Sim, W.J., et al.
Published: (2019)

The role of TGFβ in human cancers
by: Wong, Shew-Fung, et al.
Published: (2001)

USP26 regulates TGF-ß signaling by deubiquitinating and stabilizing SMAD7
by: Kit Leng Lui, S., et al.
Published: (2017)

Author Correction: c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression (Nature Communications, (2019), 10, 1, (4349), 10.1038/s41467-019-12241-2)
by: Sim, W.J., et al.
Published: (2019)

TGFβ-1 and ALK5 inhibitor treatment affects expressions of TGF β signalling pathway associated molecules in SHED cultured in keratinocyte growth medium
by: Mokhtar@Makhtar, Khairani Idah, et al.
Published: (2015)

c-Met activation leads to the establishment of a TGF-B receptor regulatory network required for bladder cancer invasion
by: Eichhorn, Pieter, et al.
Published: (2018)

Relationship between tumour-associated macrophages, CD8+ and IL17+ Cells, TGF-β, TGF-βRII, IL-17R and WNT signaling in colorectal carcinoma
by: Chai, Boon Yean
Published: (2018)

Investigating a role for heterotrimeric G-proteins in activating TGFβ in asthma
by: Middlewick, Robert James
Published: (2020)

Myb via TGFβ is required for collagen type 1 production and skin integrity
by: Sampurno, S., et al.
Published: (2015)

TGF-β-induced fibrosis: a review on the underlying mechanism and potential therapeutic strategies
by: Ong, Chun Hao, et al.
Published: (2021)

Baeckea frutescens L. Promotes wound healing by upregulating expression of TGF-β, IL-1 β, VEGF and MMP-2
by: Safwan Kamarazaman, Ihsan, et al.
Published: (2024)

Tgf-β stimulated glycosaminoglycan (GAG) biosynthetic gene expression in vascular smooth muscle cells
by: Rostam, Muhamad Ashraf, et al.
Published: (2013)

Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population
by: Azadeh, Emami
Published: (2012)

TGF-β superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development
by: Japa, Ornampai, et al.
Published: (2015)

The transcriptional regulation of VEGF production from pulmonary artery smooth muscle cells by TGFβ1
by: Clifford, Rachel
Published: (2009)

Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis
by: Calver, J.F.
Published: (2023)

Effect Of Tualang Honey Treatment On Human Keloid And Normal Fibroblast And Its Relationship With TGF-Β Expression
by: Mohamad Shah, Nurul Syazana
Published: (2011)

Protein expression of TGF-β, SMAD2 and RUNX3 in normal stomach, chronic gastritis and gastric adenocarcinoma
by: Ismail, Ahmad Zharif
Published: (2016)

Expression of P-selectin, TXA2, TGF-β1 and PDGF-AB in the Presence of Bioadhesive Chitosan Derivatives
by: Periayah, Mercy Halleluyah, et al.
Published: (2014)

Myocardial fibrosis induced by nonylphenol and its regulatory effect on the TGF-β1/LIMK1 signaling pathway
by: Guo, Mei, et al.
Published: (2024)

Flavopiridol inhibits TGF-β-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2
by: Rostam, Muhamad Ashraf, et al.
Published: (2018)

The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle
by: Rostam, Muhamad Ashraf, et al.
Published: (2016)

Inflammatory role of transforming growth factor beta-1 (TGF-β1) in multistep progression of gastric oncogenesis: an immunohistochemical study
by: Ismail, Ahmad Zharif, et al.
Published: (2015)

Post-transcriptional regulatory crosstalk between micrornas and canonical TGF-β/BMP signalling cascades on osteoblast lineage: a comprehensive review
by: Loh, Hui-Yi, et al.
Published: (2023)

Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33–mediated macrophage polarization and emphysema
by: John, Alison, E., et al.
Published: (2016)

Evolution of the TGF-beta superfamily with emphasis on Nodal
by: Shen, Yuan
Published: (2014)

Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation
by: Pasini, Alice, et al.
Published: (2018)

A central bioactive region of LTBP-2 stimulates the expression of TGF-β1 in fibroblasts via akt and p38 signalling pathways
by: Sideek, Mohamed Arshad, et al.
Published: (2017)

Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis
by: Muthuri, Stella G., et al.
Published: (2013)

Relationship between breast milk sCD14, TGF-β1 and total IgA in the first month and development of eczema during infancy
by: Ismail, Intan Hakimah, et al.
Published: (2013)

Lignosus rhinocerotis extract ameliorates airway inflammation and remodelling via attenuation of TGF-β1 and Activin A in a prolonged induced allergic asthma model
by: Muhamad, Siti-Aminah, et al.
Published: (2023)

2-methoxyestradiol TPGS micelles attenuate cyclosporine A-induced nephrotoxicity in rats through inhibition of TGF-β1 and p-ERK1/2 axis
by: Al-Rabia, Mohammed W., et al.
Published: (2022)

A comparison study on aqueous humor transforming growth factor-beta (TGF-β) and vascular endothelial growth factor (VEGF) level in primary glaucoma patients and controls
by: Samsudin, Norhayaty
Published: (2017)

Supplementation of TGF-Beta3 in low serum media promotes chondrogenesis of BMSCs
by: Alfaqeh, Hamoud Hussein Mohammed, et al.
Published: (2017)

Supplementation of TGF-Beta3 in low serum media promotes chondrogenesis of BMSCs
by: Alfaqeh, Hamoud Hussein, et al.
Published: (2017)

Immunoexpression of TGF-b in giant cell tumour, central and peripheral giant cell lesions
by: Abdul Jabbar, Omar, et al.
Published: (2015)

Study of association of TGF-ß1 polymorphism with breast density in a tertiary medical center of Malaysia
by: Wan Rohani Wan Taib,, et al.
Published: (2017)

The roles of ubiquitin modifying enzymes in neoplastic disease
by: Kumari, N., et al.
Published: (2017)

Exploring the Effects of the Long Noncoding RNA MIR205HG on PI3K Inhibitor Resistance in Breast Cancer
by: Vasilevski, Natali
Published: (2025)

Cannot write session to /tmp/vufind_sessions/sess_4jl2v5j8a7ffst113p1iikdrm3