Clinical and Imaging Features of Primary Cardiac Angiosarcoma

This study aims to explore computed tomography (CT) and magnetic resonance imaging (MRI) features of patients diagnosed with primary cardiac angiosarcoma. The study involved the analysis of 12 patients diagnosed with primary cardiac angiosarcoma who underwent non-contrast (8/12) or contrast-enhan...

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Main Authors: Chen, Y., Li, Y., Zhang, N., Shang, J., Li, Xiaodan, Liu, J., Xu, L., Liu, D., Sun, Zhonghua, Wen, Z.
Format: Journal Article
Language:English
Published: MDPI AG 2020
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/81258
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author Chen, Y.
Li, Y.
Zhang, N.
Shang, J.
Li, Xiaodan
Liu, J.
Xu, L.
Liu, D.
Sun, Zhonghua
Wen, Z.
author_facet Chen, Y.
Li, Y.
Zhang, N.
Shang, J.
Li, Xiaodan
Liu, J.
Xu, L.
Liu, D.
Sun, Zhonghua
Wen, Z.
author_sort Chen, Y.
building Curtin Institutional Repository
collection Online Access
description This study aims to explore computed tomography (CT) and magnetic resonance imaging (MRI) features of patients diagnosed with primary cardiac angiosarcoma. The study involved the analysis of 12 patients diagnosed with primary cardiac angiosarcoma who underwent non-contrast (8/12) or contrast-enhanced CT (10/12) or MRI (4/12). Imaging appearances, including the tumor location and adjacent infiltration, were analyzed. All 12 lesions were located in the right atrium with a broad base. Adjacent invasion including the tricuspid valve and right ventricle (2/12), inferior or superior vena cava (2/12), pericardium (10/12), and right coronary artery (7/12) was common. On unenhanced CT scans, tumors in two patients were homogeneous in density, whereas the others were inhomogeneous. Ten patients showed heterogeneous enhancement. The enhancement pattern showed no direct correlation with the di erentiation degree of the tumor. Four lesions manifested as heterogeneous intensity, with hyperintense hemorrhage foci on both T1- and T2-weighted MRI. Three showed rim enhancement and one showed patchy enhancement. Primary cardiac angiosarcoma often involves the right side of the heart with infiltration of peripheral structures. CT features include typical inhomogeneous density on unenhanced scans and heterogeneous centripetal enhancement on enhanced scans. A cauliflower-like appearance on both T1- and T2-weighted MRI is common. The characteristic enhancement pattern of MRI remains to be determined
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spelling curtin-20.500.11937-812582021-01-07T07:46:46Z Clinical and Imaging Features of Primary Cardiac Angiosarcoma Chen, Y. Li, Y. Zhang, N. Shang, J. Li, Xiaodan Liu, J. Xu, L. Liu, D. Sun, Zhonghua Wen, Z. 1102 - Cardiorespiratory Medicine And Haematology This study aims to explore computed tomography (CT) and magnetic resonance imaging (MRI) features of patients diagnosed with primary cardiac angiosarcoma. The study involved the analysis of 12 patients diagnosed with primary cardiac angiosarcoma who underwent non-contrast (8/12) or contrast-enhanced CT (10/12) or MRI (4/12). Imaging appearances, including the tumor location and adjacent infiltration, were analyzed. All 12 lesions were located in the right atrium with a broad base. Adjacent invasion including the tricuspid valve and right ventricle (2/12), inferior or superior vena cava (2/12), pericardium (10/12), and right coronary artery (7/12) was common. On unenhanced CT scans, tumors in two patients were homogeneous in density, whereas the others were inhomogeneous. Ten patients showed heterogeneous enhancement. The enhancement pattern showed no direct correlation with the di erentiation degree of the tumor. Four lesions manifested as heterogeneous intensity, with hyperintense hemorrhage foci on both T1- and T2-weighted MRI. Three showed rim enhancement and one showed patchy enhancement. Primary cardiac angiosarcoma often involves the right side of the heart with infiltration of peripheral structures. CT features include typical inhomogeneous density on unenhanced scans and heterogeneous centripetal enhancement on enhanced scans. A cauliflower-like appearance on both T1- and T2-weighted MRI is common. The characteristic enhancement pattern of MRI remains to be determined 2020 Journal Article http://hdl.handle.net/20.500.11937/81258 10.3390/diagnostics10100776 English http://creativecommons.org/licenses/by/4.0/ MDPI AG fulltext
spellingShingle 1102 - Cardiorespiratory Medicine And Haematology
Chen, Y.
Li, Y.
Zhang, N.
Shang, J.
Li, Xiaodan
Liu, J.
Xu, L.
Liu, D.
Sun, Zhonghua
Wen, Z.
Clinical and Imaging Features of Primary Cardiac Angiosarcoma
title Clinical and Imaging Features of Primary Cardiac Angiosarcoma
title_full Clinical and Imaging Features of Primary Cardiac Angiosarcoma
title_fullStr Clinical and Imaging Features of Primary Cardiac Angiosarcoma
title_full_unstemmed Clinical and Imaging Features of Primary Cardiac Angiosarcoma
title_short Clinical and Imaging Features of Primary Cardiac Angiosarcoma
title_sort clinical and imaging features of primary cardiac angiosarcoma
topic 1102 - Cardiorespiratory Medicine And Haematology
url http://hdl.handle.net/20.500.11937/81258