Formulation of choline chloride/ascorbic acid natural deep eutectic solvent: Characterization, solubilization capacity and antioxidant property
In the present study, natural deep eutectic solvent composed of choline chloride and ascorbic acid (CHCL/AA NADES) was formulated for enhancing the solubility and antioxidant properties of antioxidant extracts from fruit wastes of Mangifera pajang. The solubilities of Mangifera pajang's antioxi...
| Main Authors: | , , , , |
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| Format: | Journal Article |
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Elsevier
2020
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| Online Access: | http://hdl.handle.net/20.500.11937/81073 |
| _version_ | 1848764311813488640 |
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| author | Chan, Stephanie Ling, Jordy Chan, Yen San Nandong, Jobrun Ho, B.K. |
| author_facet | Chan, Stephanie Ling, Jordy Chan, Yen San Nandong, Jobrun Ho, B.K. |
| author_sort | Chan, Stephanie |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | In the present study, natural deep eutectic solvent composed of choline chloride and ascorbic acid (CHCL/AA NADES) was formulated for enhancing the solubility and antioxidant properties of antioxidant extracts from fruit wastes of Mangifera pajang. The solubilities of Mangifera pajang's antioxidant extracts in water and CHCL/AA NADES at different water contents (0–50 wt%) were investigated. It was observed that the antioxidant extracts were most soluble in the CHCL/AA NADES with 10 wt% of water, and the concentration of antioxidant was found to be approximately 15% and 4% as compared to water and pure CHCL/AA NADES, respectively. The positive effect of water on NADES can be related to the reduced viscosity of NADES, where the viscosity decreased up to 74% upon addition of water. Aside from that, all the tested CHCL/AA NADES enhanced the antioxidant capacity of antioxidant extracts by 1.3–14.64% compared to the antioxidant extracts in water. This finding highlights the role of CHCL/AA NADES as an antioxidant capacity enhancer. Noteworthy, the antioxidant extracts solubilized in the CHCL/AA NADES system formed a nano-scale cluster structure, as depicted by the TEM image, suggesting that the CHCL/AA NADES could potentially use in nanoformulation that provides protection to the antioxidant extracts. |
| first_indexed | 2025-11-14T11:17:21Z |
| format | Journal Article |
| id | curtin-20.500.11937-81073 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T11:17:21Z |
| publishDate | 2020 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-810732021-08-25T00:47:13Z Formulation of choline chloride/ascorbic acid natural deep eutectic solvent: Characterization, solubilization capacity and antioxidant property Chan, Stephanie Ling, Jordy Chan, Yen San Nandong, Jobrun Ho, B.K. In the present study, natural deep eutectic solvent composed of choline chloride and ascorbic acid (CHCL/AA NADES) was formulated for enhancing the solubility and antioxidant properties of antioxidant extracts from fruit wastes of Mangifera pajang. The solubilities of Mangifera pajang's antioxidant extracts in water and CHCL/AA NADES at different water contents (0–50 wt%) were investigated. It was observed that the antioxidant extracts were most soluble in the CHCL/AA NADES with 10 wt% of water, and the concentration of antioxidant was found to be approximately 15% and 4% as compared to water and pure CHCL/AA NADES, respectively. The positive effect of water on NADES can be related to the reduced viscosity of NADES, where the viscosity decreased up to 74% upon addition of water. Aside from that, all the tested CHCL/AA NADES enhanced the antioxidant capacity of antioxidant extracts by 1.3–14.64% compared to the antioxidant extracts in water. This finding highlights the role of CHCL/AA NADES as an antioxidant capacity enhancer. Noteworthy, the antioxidant extracts solubilized in the CHCL/AA NADES system formed a nano-scale cluster structure, as depicted by the TEM image, suggesting that the CHCL/AA NADES could potentially use in nanoformulation that provides protection to the antioxidant extracts. 2020 Journal Article http://hdl.handle.net/20.500.11937/81073 10.1016/j.lwt.2020.110096 http://creativecommons.org/licenses/by-nc-nd/4.0/ Elsevier fulltext |
| spellingShingle | Chan, Stephanie Ling, Jordy Chan, Yen San Nandong, Jobrun Ho, B.K. Formulation of choline chloride/ascorbic acid natural deep eutectic solvent: Characterization, solubilization capacity and antioxidant property |
| title | Formulation of choline chloride/ascorbic acid natural deep eutectic solvent: Characterization, solubilization capacity and antioxidant property |
| title_full | Formulation of choline chloride/ascorbic acid natural deep eutectic solvent: Characterization, solubilization capacity and antioxidant property |
| title_fullStr | Formulation of choline chloride/ascorbic acid natural deep eutectic solvent: Characterization, solubilization capacity and antioxidant property |
| title_full_unstemmed | Formulation of choline chloride/ascorbic acid natural deep eutectic solvent: Characterization, solubilization capacity and antioxidant property |
| title_short | Formulation of choline chloride/ascorbic acid natural deep eutectic solvent: Characterization, solubilization capacity and antioxidant property |
| title_sort | formulation of choline chloride/ascorbic acid natural deep eutectic solvent: characterization, solubilization capacity and antioxidant property |
| url | http://hdl.handle.net/20.500.11937/81073 |