Oral Contraceptive Use Influences On-Kinetic Adaptations to Sprint Interval Training in Recreationally-Active Women
© Copyright © 2020 Schaumberg, Stanley, Jenkins, Hume, Janse de Jonge, Emmerton and Skinner. Introduction: Oral contraceptive (OC) use influences peak exercise responses to training, however, the influence of OC on central and peripheral adaptations to exercise training are unknown. This study i...
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| Format: | Journal Article |
| Language: | English |
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FRONTIERS MEDIA SA
2020
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| Online Access: | http://hdl.handle.net/20.500.11937/81001 |
| _version_ | 1848764304977821696 |
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| author | Schaumberg, M.A. Stanley, J. Jenkins, D.G. Hume, E.A. Janse de Jonge, X.A.K. Emmerton, Lynne Skinner, T.L. |
| author_facet | Schaumberg, M.A. Stanley, J. Jenkins, D.G. Hume, E.A. Janse de Jonge, X.A.K. Emmerton, Lynne Skinner, T.L. |
| author_sort | Schaumberg, M.A. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © Copyright © 2020 Schaumberg, Stanley, Jenkins, Hume, Janse de Jonge, Emmerton and Skinner.
Introduction: Oral contraceptive (OC) use influences peak exercise responses to training, however, the influence of OC on central and peripheral adaptations to exercise training are unknown. This study investigated the influence of OC use on changes in time-to-fatigue, pulmonary oxygen uptake, cardiac output, and heart rate on-kinetics, as well as tissue saturation index to 4 weeks of sprint interval training in recreationally active women. Methods: Women taking an oral contraceptive (OC; n = 25) or experiencing natural menstrual cycles (MC; n = 22) completed an incremental exercise test to volitional exhaustion followed by a square-wave step-transition protocol to moderate (90% of power output at ventilatory threshold) and high intensity (Δ50% of power output at ventilatory threshold) exercise on two separate occasions. Time-to-fatigue, pulmonary oxygen uptake on-kinetics, cardiac output, and heart rate on-kinetics, and tissue saturation index responses were assessed prior to, and following 12 sessions of sprint interval training (10 min × 1 min efforts at 100–120% PPO in a 1:2 work:rest ratio) completed over 4 weeks. Results: Time-to-fatigue increased in both groups following training (p < 0.001), with no difference between groups. All cardiovascular on-kinetic parameters improved to the same extent following training in both groups. Greater improvements in pulmonary oxygen up-take kinetics were seen at both intensities in the MC group (p < 0.05 from pre-training) but were blunted in the OC group (p > 0.05 from pre-training). In contrast, changes in tissue saturation index were greater in the OC group at both intensities (p < 0.05); with the MC group showing no changes at either intensity. Discussion: Oral contraceptive use may reduce central adaptations to sprint interval training in women without influencing improvements in exercise performance - potentially due to greater peripheral adaptation. This may be due to the influence of exogenous oestradiol and progestogen on cardiovascular function and skeletal muscle blood flow. Further investigation into female-specific influences on training adaptation and exercise performance is warranted. |
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| format | Journal Article |
| id | curtin-20.500.11937-81001 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T11:17:14Z |
| publishDate | 2020 |
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| spelling | curtin-20.500.11937-810012021-01-07T07:46:46Z Oral Contraceptive Use Influences On-Kinetic Adaptations to Sprint Interval Training in Recreationally-Active Women Schaumberg, M.A. Stanley, J. Jenkins, D.G. Hume, E.A. Janse de Jonge, X.A.K. Emmerton, Lynne Skinner, T.L. Science & Technology Life Sciences & Biomedicine Physiology female training adaptation ovarian hormones oral contraceptive (OC) exogenous hormones cardiorespiratory time-to-fatigue OXYGEN-UPTAKE KINETICS MODERATE-INTENSITY EXERCISE PULMONARY O-2 UPTAKE MUSCLE DEOXYGENATION CARDIAC-OUTPUT PHYSIOLOGICAL ADAPTATIONS SKELETAL-MUSCLE BLOOD-FLOW PERFORMANCE CYCLE © Copyright © 2020 Schaumberg, Stanley, Jenkins, Hume, Janse de Jonge, Emmerton and Skinner. Introduction: Oral contraceptive (OC) use influences peak exercise responses to training, however, the influence of OC on central and peripheral adaptations to exercise training are unknown. This study investigated the influence of OC use on changes in time-to-fatigue, pulmonary oxygen uptake, cardiac output, and heart rate on-kinetics, as well as tissue saturation index to 4 weeks of sprint interval training in recreationally active women. Methods: Women taking an oral contraceptive (OC; n = 25) or experiencing natural menstrual cycles (MC; n = 22) completed an incremental exercise test to volitional exhaustion followed by a square-wave step-transition protocol to moderate (90% of power output at ventilatory threshold) and high intensity (Δ50% of power output at ventilatory threshold) exercise on two separate occasions. Time-to-fatigue, pulmonary oxygen uptake on-kinetics, cardiac output, and heart rate on-kinetics, and tissue saturation index responses were assessed prior to, and following 12 sessions of sprint interval training (10 min × 1 min efforts at 100–120% PPO in a 1:2 work:rest ratio) completed over 4 weeks. Results: Time-to-fatigue increased in both groups following training (p < 0.001), with no difference between groups. All cardiovascular on-kinetic parameters improved to the same extent following training in both groups. Greater improvements in pulmonary oxygen up-take kinetics were seen at both intensities in the MC group (p < 0.05 from pre-training) but were blunted in the OC group (p > 0.05 from pre-training). In contrast, changes in tissue saturation index were greater in the OC group at both intensities (p < 0.05); with the MC group showing no changes at either intensity. Discussion: Oral contraceptive use may reduce central adaptations to sprint interval training in women without influencing improvements in exercise performance - potentially due to greater peripheral adaptation. This may be due to the influence of exogenous oestradiol and progestogen on cardiovascular function and skeletal muscle blood flow. Further investigation into female-specific influences on training adaptation and exercise performance is warranted. 2020 Journal Article http://hdl.handle.net/20.500.11937/81001 10.3389/fphys.2020.00629 English http://creativecommons.org/licenses/by/4.0/ FRONTIERS MEDIA SA fulltext |
| spellingShingle | Science & Technology Life Sciences & Biomedicine Physiology female training adaptation ovarian hormones oral contraceptive (OC) exogenous hormones cardiorespiratory time-to-fatigue OXYGEN-UPTAKE KINETICS MODERATE-INTENSITY EXERCISE PULMONARY O-2 UPTAKE MUSCLE DEOXYGENATION CARDIAC-OUTPUT PHYSIOLOGICAL ADAPTATIONS SKELETAL-MUSCLE BLOOD-FLOW PERFORMANCE CYCLE Schaumberg, M.A. Stanley, J. Jenkins, D.G. Hume, E.A. Janse de Jonge, X.A.K. Emmerton, Lynne Skinner, T.L. Oral Contraceptive Use Influences On-Kinetic Adaptations to Sprint Interval Training in Recreationally-Active Women |
| title | Oral Contraceptive Use Influences On-Kinetic Adaptations to Sprint Interval Training in Recreationally-Active Women |
| title_full | Oral Contraceptive Use Influences On-Kinetic Adaptations to Sprint Interval Training in Recreationally-Active Women |
| title_fullStr | Oral Contraceptive Use Influences On-Kinetic Adaptations to Sprint Interval Training in Recreationally-Active Women |
| title_full_unstemmed | Oral Contraceptive Use Influences On-Kinetic Adaptations to Sprint Interval Training in Recreationally-Active Women |
| title_short | Oral Contraceptive Use Influences On-Kinetic Adaptations to Sprint Interval Training in Recreationally-Active Women |
| title_sort | oral contraceptive use influences on-kinetic adaptations to sprint interval training in recreationally-active women |
| topic | Science & Technology Life Sciences & Biomedicine Physiology female training adaptation ovarian hormones oral contraceptive (OC) exogenous hormones cardiorespiratory time-to-fatigue OXYGEN-UPTAKE KINETICS MODERATE-INTENSITY EXERCISE PULMONARY O-2 UPTAKE MUSCLE DEOXYGENATION CARDIAC-OUTPUT PHYSIOLOGICAL ADAPTATIONS SKELETAL-MUSCLE BLOOD-FLOW PERFORMANCE CYCLE |
| url | http://hdl.handle.net/20.500.11937/81001 |