Synthesis of Distally‐Bridged Chiral Resorcinarene Crowns.

Our interest in the potential of chiral tetramethoxy-resorcinarene as agents for chiral recognition has led us to synthesise twelve distally-bridged chiral resorcinarene crowns. The fascinating architecture of these partially-enclosed chiral basket molecules is evident in the solid-state structures...

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Bibliographic Details
Main Authors: Mocerino, Mauro, Tan, Daniel A, McIldowie, Matthew J, Massera, Chiara
Format: Journal Article
Published: Wiley-Blackwell 2020
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/80331
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Summary:Our interest in the potential of chiral tetramethoxy-resorcinarene as agents for chiral recognition has led us to synthesise twelve distally-bridged chiral resorcinarene crowns. The fascinating architecture of these partially-enclosed chiral basket molecules is evident in the solid-state structures which have been determined by single crystal X-ray crystallography. Moreover, the enantiomers of these chiral resorcinarene crowns have been resolved via diastereomeric resolution, with the absolute configuration of the diastereomers being determined by X-ray crystallography. This work enables further exploration of these enantio-pure chiral baskets as possible chiral resolving agents.