Confounding effects of gavage in mice: Impaired respiratory structure and function

The authors talk about the confounding effects of gavage in mice. He said that gavage is the most widely used method for precise oral dosing in experimental studies involving rodents. In the hands of a skilled operator, the procedure is rapid and allows for a precise volume of a substance to be deli...

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Main Authors: Larcombe, Alexander, Wang, K.C.W., Phan, J.A., Berry, L.J., Noble, P.B.
Format: Journal Article
Language:English
Published: AMER THORACIC SOC 2019
Subjects:
Online Access:http://purl.org/au-research/grants/nhmrc/1128231
http://hdl.handle.net/20.500.11937/80322
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author Larcombe, Alexander
Wang, K.C.W.
Phan, J.A.
Berry, L.J.
Noble, P.B.
author_facet Larcombe, Alexander
Wang, K.C.W.
Phan, J.A.
Berry, L.J.
Noble, P.B.
author_sort Larcombe, Alexander
building Curtin Institutional Repository
collection Online Access
description The authors talk about the confounding effects of gavage in mice. He said that gavage is the most widely used method for precise oral dosing in experimental studies involving rodents. In the hands of a skilled operator, the procedure is rapid and allows for a precise volume of a substance to be delivered directly to the stomach, where it can be absorbed. Gavage is advantageous in situations where the substance to be delivered cannot be incorporated into feed or is unpalatable. Of particular interest to the current readership is the common use of gavage in studies with a respiratory focus.
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publishDate 2019
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spelling curtin-20.500.11937-803222023-10-04T06:33:34Z Confounding effects of gavage in mice: Impaired respiratory structure and function Larcombe, Alexander Wang, K.C.W. Phan, J.A. Berry, L.J. Noble, P.B. Science & Technology Life Sciences & Biomedicine Biochemistry & Molecular Biology Cell Biology Respiratory System ORAL GAVAGE AIRWAY ASTHMA RESPONSES MODEL The authors talk about the confounding effects of gavage in mice. He said that gavage is the most widely used method for precise oral dosing in experimental studies involving rodents. In the hands of a skilled operator, the procedure is rapid and allows for a precise volume of a substance to be delivered directly to the stomach, where it can be absorbed. Gavage is advantageous in situations where the substance to be delivered cannot be incorporated into feed or is unpalatable. Of particular interest to the current readership is the common use of gavage in studies with a respiratory focus. 2019 Journal Article http://hdl.handle.net/20.500.11937/80322 10.1165/rcmb.2019-0242LE English http://purl.org/au-research/grants/nhmrc/1128231 http://purl.org/au-research/grants/nhmrc/1090888 AMER THORACIC SOC restricted
spellingShingle Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Cell Biology
Respiratory System
ORAL GAVAGE
AIRWAY
ASTHMA
RESPONSES
MODEL
Larcombe, Alexander
Wang, K.C.W.
Phan, J.A.
Berry, L.J.
Noble, P.B.
Confounding effects of gavage in mice: Impaired respiratory structure and function
title Confounding effects of gavage in mice: Impaired respiratory structure and function
title_full Confounding effects of gavage in mice: Impaired respiratory structure and function
title_fullStr Confounding effects of gavage in mice: Impaired respiratory structure and function
title_full_unstemmed Confounding effects of gavage in mice: Impaired respiratory structure and function
title_short Confounding effects of gavage in mice: Impaired respiratory structure and function
title_sort confounding effects of gavage in mice: impaired respiratory structure and function
topic Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Cell Biology
Respiratory System
ORAL GAVAGE
AIRWAY
ASTHMA
RESPONSES
MODEL
url http://purl.org/au-research/grants/nhmrc/1128231
http://purl.org/au-research/grants/nhmrc/1128231
http://hdl.handle.net/20.500.11937/80322