Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma

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Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma

Airway smooth muscle (ASM) plays a major role in acute airway narrowing and reducing ASM thickness is expected to attenuate airway hyper-responsiveness and disease burden. There are two therapeutic approaches to reduce ASM thickness: (a) a direct approach, targeting specific airways, best exemplifie...

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Bibliographic Details
Main Authors:	Donovan, G.M., Wang, K.C.W., Shamsuddin, D., Mann, T.S., Henry, P.J., Larcombe, Alexander, Noble, P.B.
Format:	Journal Article
Language:	English
Published:	2020
Subjects:	airway hyper-responsiveness asthma
Online Access:	http://purl.org/au-research/grants/nhmrc/1143496 http://hdl.handle.net/20.500.11937/80313

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