Identifying the optimal donor for natural killer cell adoptive therapy to treat paediatric B- and T-cell acute lymphoblastic leukaemia.

Identifying the optimal donor for natural killer cell adoptive therapy to treat paediatric B- and T-cell acute lymphoblastic leukaemia.

Objectives: Natural killer (NK) cells are an attractive source of cells for an 'off the shelf' cellular therapy because of their innate capacity to target malignant cells, and ability to be transferred between donors and patients. However, since not all NK cells are equally effective at ta...

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Bibliographic Details
Main Authors: Foley, Bree, Ta, Clara, Barnes, Samantha, de Jong, Emma, Nguyen, Michelle, Cheung, Laurence, Buzzai, Anthony, Wagner, Teagan, Wylie, Ben, Fernandez, Sonia, Cruickshank, Mark, Endersby, Raelene, Kees, Ursula, Waithman, Jason
Format: Journal Article
Language:English
Published: 2020
Subjects:
acute lymphoblastic leukaemia
cellular therapy
cytomegalovirus
natural killer cells
Online Access:http://hdl.handle.net/20.500.11937/80259

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